ArticleCureus2025
Microscope-Integrated Optical Coherence Tomography-Guided Rapid Resolution of Acute Hydrops.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Inadvertent peripheral big-bubble formation following wound hydration.Eye (London, England) · 2026Article
- Air-Assisted Dome Drainage in Acute Corneal Hydrops: A 3D-OCT-Guided Approach.Bioengineering (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An 18-year-old boy presented with blurred visual acuity in the left eye for three days associated with mild pain and photophobia. On examination, he had diffuse corneal stromal edema. Anterior segment optical coherence tomography (AS-OCT) revealed stromal edema with a large hypodense fluid pocket in the posterior stroma. A diagnosis of acute hydrops with an intrastromal cleft in the left eye was made, and he was planned for intracameral gas injection. Intraoperatively, microscope-integrated OCT (Mi-OCT)-guided intracameral isoexpansile sulphur hexafluoride(SF6) was injected ensuring an 80% fill of the anterior chamber. Mi-OCT-assisted venting incision with drainage of stromal fluid clefts was done. On the first postoperative day, the fluid pocket and stromal edema resolved completely. At six weeks' follow-up, the central cornea remained clear with the formation of a paracentral scar. Thus, intracameral gas combined with stromal cleft drainage appears to be a highly effective management option for acute hydrops with a single large stromal fluid cleft. Intraoperative OCT (Mi-OCT) can guide real-time drainage of intrastromal fluid clefts, facilitating the closure of focal Descemet's membrane (DM) defects and enabling early visual rehabilitation, as demonstrated in this case as early as one-day postprocedure.
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Registered trials
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