Evidence map›Paper›PMID 39916976›Full record

ArticlePhotoacoustics2025

Enhanced clinical photoacoustic vascular imaging through a skin localization network and adaptive weighting.

Chuqin Huang, Emily Zheng, Wenhan Zheng, Huijuan Zhang, Yanda Cheng, Xiaoyu Zhang, Varun Shijo, Robert W Bing, Isabel Komornicki, Linda M Harris and 5 more

Abstract read
In one paragraph

Article in Photoacoustics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Chuqin HuangDepartment of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14228, United States.
Emily ZhengDepartment of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14228, United States.
Wenhan ZhengDepartment of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14228, United States.
Huijuan ZhangDepartment of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14228, United States.
Yanda ChengDepartment of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14228, United States.
Xiaoyu ZhangDepartment of Computer Science and Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14228, United States.
Varun ShijoDepartment of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14228, United States.
Robert W BingDepartment of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14228, United States.
Isabel KomornickiDepartment of Surgery, University at Buffalo, The State University of New York, Buffalo, NY 14228, United States.
Linda M HarrisDepartment of Surgery, University at Buffalo, The State University of New York, Buffalo, NY 14228, United States.
Ermelinda BonaccioDepartment of Breast Imaging, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, United States.
Kazuaki TakabeDepartment of Surgery, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, United States.
Emma ZhangDepartment of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14228, United States.
Wenyao XuDepartment of Computer Science and Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14228, United States.
Jun XiaDepartment of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14228, United States.

Funding

mHealth Technologies for Assessing Blood Perfusion in Chronic WoundsR01EB035188 · NIBIB · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI Wenyao Xu · 2024 to 2026
$2.0M
Development of photoacoustic tomography for non-invasive, label-free imaging of tissue perfusion in chronic woundsR01EB028978 · NIBIB · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI XIA, JUN · 2021 to 2024
$1.6M
Multiparametric photoacoustic and ultrasonic imaging of the breast in cranial-caudal viewR01EB029596 · NIBIB · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI XIA, JUN · 2020 to 2023
$1.4M
NIBIB NIH HHS R01 EB028978NIBIB NIH HHS R01 EB029596NIBIB NIH HHS R01 EB035188
6 · The paper itself

Abstract

Photoacoustic tomography (PAT) is an emerging imaging modality with widespread applications in both preclinical and clinical studies. Despite its promising capabilities to provide high-resolution images, the visualization of vessels might be hampered by skin signals and attenuation in tissues. In this study, we have introduced a framework to retrieve deep vessels. It combines a deep learning network to segment skin layers and an adaptive weighting algorithm to compensate for attenuation. Evaluation of enhancement using vessel occupancy metrics and signal-to-noise ratio (SNR) demonstrates that the proposed method significantly recovers deep vessels across various body positions and skin tones. These findings indicate the method's potential to enhance quantitative analysis in preclinical and clinical photoacoustic research.

Indexed as

Deep learningImage enhancementPhotoacousticPhotoacoustic tomography

Identifiers

PMID39916976
PMCPMC11800082

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.