Improved understanding of the respiratory drive pathophysiology could lead to earlier spontaneous breathing in severe acute respiratory distress syndrome.

Fabrice Petitjeans, Sandrine Leroy, Cyrille Pichot, Marco Ghignone, Luc Quintin, Dan Longrois, Jean-Michel Constantin

Abstract read

In one paragraph

Article in European journal of anaesthesiology and intensive care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

Combining OJournal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2024
Review
Redefining ARDS: a paradigm shift.Critical care (London, England) · 2023
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fabrice PetitjeansFrom the Critical Care, Hôpital d'Instruction des Armées Desgenettes, Lyon, France (FP, LQ), Environmental Justice Program, Georgetown University, Washington, DC (SL), Hôpital Louis Pasteur, Dole (CP), Université de Paris (Diderot, Sorbonne), Hôpital Bichat and UMR 5698 and GRC 29, DMU DREAM (DL), Hôpital Pitié-Salpêtrière, Paris, France (J-MC) and JF Kennedy North Hospital, West Palm Beach, Florida, USA (MG).

Sandrine LeroyFrom the Critical Care, Hôpital d'Instruction des Armées Desgenettes, Lyon, France (FP, LQ), Environmental Justice Program, Georgetown University, Washington, DC (SL), Hôpital Louis Pasteur, Dole (CP), Université de Paris (Diderot, Sorbonne), Hôpital Bichat and UMR 5698 and GRC 29, DMU DREAM (DL), Hôpital Pitié-Salpêtrière, Paris, France (J-MC) and JF Kennedy North Hospital, West Palm Beach, Florida, USA (MG).

Cyrille PichotFrom the Critical Care, Hôpital d'Instruction des Armées Desgenettes, Lyon, France (FP, LQ), Environmental Justice Program, Georgetown University, Washington, DC (SL), Hôpital Louis Pasteur, Dole (CP), Université de Paris (Diderot, Sorbonne), Hôpital Bichat and UMR 5698 and GRC 29, DMU DREAM (DL), Hôpital Pitié-Salpêtrière, Paris, France (J-MC) and JF Kennedy North Hospital, West Palm Beach, Florida, USA (MG).

Marco GhignoneFrom the Critical Care, Hôpital d'Instruction des Armées Desgenettes, Lyon, France (FP, LQ), Environmental Justice Program, Georgetown University, Washington, DC (SL), Hôpital Louis Pasteur, Dole (CP), Université de Paris (Diderot, Sorbonne), Hôpital Bichat and UMR 5698 and GRC 29, DMU DREAM (DL), Hôpital Pitié-Salpêtrière, Paris, France (J-MC) and JF Kennedy North Hospital, West Palm Beach, Florida, USA (MG).

Luc QuintinFrom the Critical Care, Hôpital d'Instruction des Armées Desgenettes, Lyon, France (FP, LQ), Environmental Justice Program, Georgetown University, Washington, DC (SL), Hôpital Louis Pasteur, Dole (CP), Université de Paris (Diderot, Sorbonne), Hôpital Bichat and UMR 5698 and GRC 29, DMU DREAM (DL), Hôpital Pitié-Salpêtrière, Paris, France (J-MC) and JF Kennedy North Hospital, West Palm Beach, Florida, USA (MG).

Dan LongroisFrom the Critical Care, Hôpital d'Instruction des Armées Desgenettes, Lyon, France (FP, LQ), Environmental Justice Program, Georgetown University, Washington, DC (SL), Hôpital Louis Pasteur, Dole (CP), Université de Paris (Diderot, Sorbonne), Hôpital Bichat and UMR 5698 and GRC 29, DMU DREAM (DL), Hôpital Pitié-Salpêtrière, Paris, France (J-MC) and JF Kennedy North Hospital, West Palm Beach, Florida, USA (MG).

Jean-Michel ConstantinFrom the Critical Care, Hôpital d'Instruction des Armées Desgenettes, Lyon, France (FP, LQ), Environmental Justice Program, Georgetown University, Washington, DC (SL), Hôpital Louis Pasteur, Dole (CP), Université de Paris (Diderot, Sorbonne), Hôpital Bichat and UMR 5698 and GRC 29, DMU DREAM (DL), Hôpital Pitié-Salpêtrière, Paris, France (J-MC) and JF Kennedy North Hospital, West Palm Beach, Florida, USA (MG).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optimisation of the respiratory drive, as early as possible in the setting of severe acute respiratory distress syndrome (ARDS) and not its suppression, could be a new paradigm in the management of severe forms of ARDS. Severe ARDS is characterised by tachypnoea and hyperpnoea, a consequence of a high respiratory drive. Some patients require endotracheal intubation, controlled mechanical ventilation (CMV) and paralysis to prevent overt ventilatory failure and self-inflicted lung injury. Nevertheless, intubation, CMV and paralysis do GLOSSARY: Glossary and Abbreviations_SDC.

Identifiers

PMID39916810

DOI10.1097/EA9.0000000000000030

PMCPMC11783659

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.