ArticleFrontiers in endocrinology2024
The potential of the serum uric acid to high-density lipoprotein cholesterol ratio as a predictive biomarker of diabetes risk: a study based on NHANES 2005-2018.
Article in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed.
- Multi-trajectories of serum uric acid/high density lipoprotein cholesterol ratio and fasting plasma glucose in chronic kidney disease.Annals of medicine · 2026Article
- Diagnostic performance of TyG-related indices for MAFLD screening in older adults at moderate altitude: TyG-BMI showed the highest discriminatory ability.BMC gastroenterology · 2026Article
- Association between the ratio of uric acid to high-density lipoprotein cholesterol (UHR) and the abnormal risk of sarcopenia: Evidence from two large population-based surveys and interpretable machine learning-driven sarcopenia screening.Therapeutic advances in endocrinology and metabolism · 2026Article
- Association of Cumulative Average Uric Acid to HDL Cholesterol Ratio with the Risk of Rapidly Declining Renal Function: A Retrospective Community-Based Cohort Study in Shanghai Undertaken on Elderly Subjects with Hypertension and Type 2 Diabetes Mellitus Patients.Risk management and healthcare policy · 2026Article
- A comprehensive study on the uric acid to high-density cholesterol ratio influencing cardiometabolic-based chronic disease in China.Frontiers in nutrition · 2026Article
- Association between red cell distribution width-to-albumin ratio and risk of diabetic kidney disease: a cross-sectional NHANES study.BMC urology · 2025Article
- The uric acid to high density lipoprotein cholesterol ratio as a new indicator for predicting coronary slow flow phenomenon.BMC cardiovascular disorders · 2025Article
- The correlation between the uric acid to high-density lipoprotein cholesterol ratio and stroke.Frontiers in medicine · 2025Article
- Sex differences in the association between the uric acid to high density lipoprotein cholesterol ratio and mild cognitive impairment in patients with type 2 diabetes mellitus.Frontiers in nutrition · 2025Article
- A Cross-Sectional Study of the Association Between Uric Acid-to-High-Density Lipoprotein Cholesterol Ratio and Carotid Atherosclerosis in Patients with Type 2 Diabetes Mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- The relationship between dietary vitamin B1 and stroke: a machine learning analysis of NHANES data.Frontiers in nutrition · 2025Article
- Serum uric acid-to-HDL cholesterol ratio and stroke prevalence: NHANES 1999-2018 with external support from an imaging-confirmed hemorrhagic stroke dataset.Frontiers in neurologyArticle
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7 authors.
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Abstract
Previous studies have indicated an association between UHR and diabetes risk, but evidence from large-scale and diverse populations remains limited. This study aims to verify UHR's independent role in diabetes risk prediction in a large sample population and assess its applicability across different populations. We drew upon data from 30,813 participants collected during the 2005-2018 NHANES cycle. The association between UHR and the risk of diabetes was explored using multivariate logistic regression models, with key predictive factors identified through LASSO regression. Model effectiveness was evaluated through receiver operating characteristic (ROC) curves, decision curve analysis (DCA), and calibration metrics. Additionally, restricted cubic spline (RCS) and threshold effect assessments were applied to examine the nonlinear association between UHR and diabetes risk. The results showed that UHR levels were notably elevated in individuals with diabetes when compared to those without diabetes (
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