Evidence map›Paper›PMID 39916292›Full record

ArticleAmerican journal of human biology : the official journal of the Human Biology Council2025

Chronic Stress and Severe Water Insecurity During the Historic 2022 Drought in Northern Kenya Were Associated With Inflammation Among Daasanach Seminomadic Pastoralists.

Kedir Teji Roba, Hannah Jacobson, Amanda McGrosky, Srishti Sadhir, Leslie B Ford, Marcela Pfaff, Elizabeth Y Kim, Rosemary Nzunza, Matthew Douglass, David R Braun and 4 more

Abstract read
In one paragraph

Article in American journal of human biology : the official journal of the Human Biology Council, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Increased Vulnerability to Dehydration Due to Heat Stress and Drought Across Reproductive States for Pastoralist Women in Northern Kenya.American journal of human biology : the official journal of the Human Biology Council · 2026
    Article
  4. Birth Weight in the Daasanach Community of Northern Kenya and the Effect of Multiparity.American journal of human biology : the official journal of the Human Biology Council · 2026
    Article
  5. Implementation of family-centered care in Pediatric Gastroscopy.Pakistan journal of medical sciences · 2026
    Article
  6. The Ecology and Human Biology of Pastoralists: Building on the Contributions of Michael A. Little.American journal of human biology : the official journal of the Human Biology Council · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kedir Teji RobaDepartment of Biobehavioral Health, Pennsylvania State University, University Park, Pennsylvania, USA.ORCID 0000-0001-6227-9594
Hannah JacobsonDepartment of Anthropology, Northwestern University, Evanston, Illinois, USA.
Amanda McGroskyDepartment of Biology, Elon University, Elon, North Carolina, USA.ORCID 0000-0002-1110-4310
Srishti SadhirDepartment of Evolutionary Anthropology, Duke University, Durham, North Carolina, USA.ORCID 0000-0002-3689-5892
Leslie B FordDepartment of Biobehavioral Health, Pennsylvania State University, University Park, Pennsylvania, USA.ORCID 0000-0002-3904-5105
Marcela PfaffDepartment of Anthropology, Baylor University, Waco, Texas, USA.ORCID 0000-0003-2344-6294
Elizabeth Y KimDepartment of Biology, Baylor University, Waco, Texas, USA.ORCID 0000-0002-4752-5272
Rosemary NzunzaCenter for Virus Research, Kenya Medical Research Institute (KEMRI), Nairobi, Kenya.
Matthew DouglassUniversity of Nebraska-Lincoln, Lincoln, Nebraska, USA.ORCID 0000-0001-5398-6473
David R BraunCenter for the Advanced Study of Human Paleobiology, Department of Anthropology, The George Washington University, Washington, DC, USA.ORCID 0000-0002-7300-2635
Emmanuel NdiemaDepartment of Earth Sciences, National Museums of Kenya, Nairobi, Kenya.ORCID 0000-0002-1335-2924
Samuel S UrlacherDepartment of Anthropology, Baylor University, Waco, Texas, USA.ORCID 0000-0002-6489-4117
Herman PontzerDepartment of Evolutionary Anthropology, Duke University, Durham, North Carolina, USA.ORCID 0000-0003-2397-6543
Asher Y RosingerDepartment of Biobehavioral Health, Pennsylvania State University, University Park, Pennsylvania, USA.ORCID 0000-0001-9587-1447

Funding

The Population Research Institute: Development CoreP2CHD041025 · NICHD · PENNSYLVANIA STATE UNIVERSITY, THE · PI Sarah Damaske · 2016 to 2026
$9.0M
Science CoreP2CHD065563 · NICHD · DUKE UNIVERSITY · PI James Moody · 2015 to 2026
$5.7M
Training Program in Social Environments and Population HealthT32HD007514 · NICHD · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI JOHN D. ICELAND · 1999 to 2026
$5.1M
Ann Atherton Herzler Early Career Professorship in Global Health at Pennsylvania State UniversityNational Institute for Child Health and Human Development 2T32HD007514-21A1National Institute for Child Health and Human Development P2CHD041025National Science Foundation NSF CNH2-S #1924322National Science Foundation NSF REU #1852406NICHD NIH HHS P2C HD041025NICHD NIH HHS P2C HD065563NICHD NIH HHS T32 HD007514
6 · The paper itself

Abstract

objectiveExtreme climatic events, like droughts, are increasing in frequency and severity. Droughts disrupt community livelihoods and resources with serious implications for human biology. This study investigated how chronic stress, measured by fingernail cortisol concentration (FCC), and water insecurity status were predictive of C-reactive protein (CRP), a biomarker of inflammation, during a historic drought among Daasanach seminomadic pastoralists.

methodsData were collected at the height of the 2022 drought from 128 Daasanach household heads aged 16-80 years in northern Kenya using household surveys, anthropometric measurements, and dried blood spots to assess CRP levels and fingernails to assess FCC. We employed mixed-effects linear and logistic regression models to examine the relationships between log-transformed FCC, high water insecurity status measured via the Household Water Insecurity Experiences (HWISE ≥ 24) scale, and serum-equivalent CRP (log-transformed and dichotomized at mild, low-grade inflammation ≥ 1 mg/L) adjusted for covariates.

resultsThe mean serum-equivalent CRP was 4.1 mg/L and 56.3% of Daasanach adults had at least mild, low-grade inflammation. Linear models indicated that ln(FCC) was positively associated with ln(CRP) (β = 0.56, SE = 0.12; p < 0.001). Further, logistic models demonstrated that ln(FCC) (OR = 2.69, 95% CI: 1.84-3.95; p < 0.001) and high water insecurity (OR = 2.23, 95% CI: 1.34-3.72; p = 0.002) were both associated with greater odds of low-grade inflammation.

conclusionThis study provides evidence for how chronic stress and severe water insecurity may impact inflammation levels among pastoralists during drought. Since inflammation is central to cardiometabolic disease etiology, this is an additional reason to mitigate the negative health impacts of droughts and water insecurity exacerbated by climate change.

Indexed as

C-Reactive ProteinDroughtsInflammationStress, PsychologicalWater InsecurityAdolescentAdultAgedAged, 80 and overFemaleHumansHydrocortisoneKenyaMaleMiddle AgedYoung AdultC-Reactive ProteinHydrocortisonechronic stresscortisolCRPdroughtinflammationKenyapastoralismwater insecurity

Identifiers

PMID39916292
PMCPMC11803130

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.