Evidence map›Paper›PMID 39915778›Full record

ArticleBMC veterinary research2025

Dietary supplementation of Astragalus polysaccharide or its nanoparticles enhances testicular hemodynamics, echotexture, scrotal circumference, concentration of testosterone, estradiol, nitric oxide, and total antioxidant capacity, and semen quality in mature Ossimi rams.

Eman Fayez, Ali Salama, Mohamed Ahmed Ismail, Fady Sayed Youssef, Zaher Mohamed Rawash, M R Oshba, Haney Samir

Abstract read
In one paragraph

Article in BMC veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eman FayezDepartment of Theriogenology, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt.
Ali SalamaDepartment of Theriogenology, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt.
Mohamed Ahmed IsmailDepartment of Theriogenology, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt.
Fady Sayed YoussefPharmacology Department, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Zaher Mohamed RawashArtificial Insemination and Embryo Transfer Department, Animal Reproduction Research Institute (ARRI), Agriculture Research Centre (ARC), Giza, Egypt.
M R OshbaDiagnostic Imaging and Endoscopy Unit (DIEU), Animal Reproduction Research Institute (ARRI), Agriculture Research Centre (ARC), Giza, Egypt.
Haney SamirDepartment of Theriogenology, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt. Haneyvet360@cu.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated, for the first time, the potential role of Astragalus polysaccharide (APS) and APS nanoparticles on testicular blood flow (TBF) and semen quality in Ossimi rams. Fifteen sexually mature Ossimi rams were allocated randomly into two treated groups that orally administered either nano APS (2 g/ram/day; n = 5) or APS (20 g/ram/day; n = 5) for four weeks and a control group (n = 5). The nano-emulsion was prepared by adding corn oil to the APS solution, sonicated, centrifuged at 20,000 rpm, then washed 3-4 times, and vacuum dried overnight at 40 °C. The antioxidant activity of APS and APS nano-emulsion was evaluated in vitro. Blood collection and ultrasonographic assessment of the testes and supratesticular arteries (STAs) were conducted immediately before treatment (W0) and once weekly for 6 successive weeks after APS and nano APS administration (W1-W6). Serum testosterone (T) and estradiol (E

Indexed as

Astragalus PlantPolysaccharidesTestisAnimal FeedAnimalsAntioxidantsDietDietary SupplementsEstradiolMaleNanoparticlesNitric OxideScrotumSemen AnalysisSheepTestosteroneAntioxidantsEstradiolNitric OxidePolysaccharidesTestosteroneAstragalus polysaccharideEchotextureEstradiolNitric oxideRamSemen qualityTesticular hemodynamicsTestosteroneTotal antioxidant capacity

Identifiers

PMID39915778
PMCPMC11804079

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.