Evidence map›Paper›PMID 39915694›Full record

ArticleJournal of neuroendocrinology2025

Corticotropin-releasing hormone receptor 1 mediates the enhanced locomotor activity and metabolic demands to an acute thermal stress in adult zebrafish.

Zachary Shvartsburd, Mathilakath M Vijayan

Abstract read
In one paragraph

Article in Journal of neuroendocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zachary ShvartsburdDepartment of Biological Sciences, University of Calgary, Calgary, Alberta, Canada.
Mathilakath M VijayanDepartment of Biological Sciences, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-4300-1965

Funding

Natural Sciences and Engineering Research Council of Canada RGPIN-2019-06291
6 · The paper itself

Abstract

We recently showed that Crh-Crhr1 signalling is essential for acute stress-related locomotor activity in zebrafish larvae. However, the possibility that Crhr1 activation may also initiate the acute metabolic demands for stress coping was unexplored. Here, we tested the hypothesis that Crhr1 signalling is essential for the thermal stressor-induced increases in the acute metabolic rate, a key response for coping with the enhanced energy demands during stress. We tested this by using a wildtype (WT) and a ubiquitous Crhr1 knockout (crhr1

Indexed as

Energy MetabolismHeat-Shock ResponseLocomotionReceptors, Corticotropin-Releasing HormoneStress, PhysiologicalZebrafishZebrafish ProteinsAnimalsCRF Receptor, Type 1HydrocortisoneMotor ActivitySignal TransductionCRF Receptor, Type 1HydrocortisoneReceptors, Corticotropin-Releasing HormoneZebrafish ProteinscortisolHPI axisintermediary metabolismstress‐related behaviourstress response

Identifiers

PMID39915694
PMCPMC11975798

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.