Evidence map›Paper›PMID 39915669›Full record

ArticleScientific reports2025

Expanding diversity in developmental profiles of very-low-birth-weight infants during 6 years after birth.

Kyoko Watanabe, Reina Ogata, Kenta Kajiwara, Hirosuke Inoue, Yoshihiro Sakemi, Masako Ichiyama, Toru Sawano, Kazuaki Yasuoka, Takahide Watabe, Hiroaki Kurata and 9 more

Abstract read
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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Kyoko WatanabeDepartment of Pediatrics, NHO Kokura Medical Center, Kitakyushu, Japan.
Reina OgataDepartment of Pediatrics, NHO Kokura Medical Center, Kitakyushu, Japan.
Kenta KajiwaraDepartment of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Hirosuke InoueDepartment of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Yoshihiro SakemiDepartment of Pediatrics, NHO Kokura Medical Center, Kitakyushu, Japan.
Masako IchiyamaDepartment of Pediatrics, NHO Kokura Medical Center, Kitakyushu, Japan.
Toru SawanoDepartment of Pediatrics, NHO Kokura Medical Center, Kitakyushu, Japan.
Kazuaki YasuokaDepartment of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Takahide WatabeDepartment of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Hiroaki KurataDepartment of Pediatrics, NHO Kokura Medical Center, Kitakyushu, Japan.
Toshinori NakashimaDepartment of Pediatrics, NHO Kokura Medical Center, Kitakyushu, Japan.
Yuri SonodaDepartment of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Pin Fee ChongDepartment of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Satoshi AkamineDepartment of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Masayuki OchiaiDepartment of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Takuro OhnoDepartment of Pediatrics, NHO Kokura Medical Center, Kitakyushu, Japan.
Hironori YamashitaDepartment of Pediatrics, NHO Kokura Medical Center, Kitakyushu, Japan.
Yasunari SakaiDepartment of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. sakai.yasunari.530@m.kyushu-u.ac.jp.ORCID 0000-0002-5747-8692
Shouichi OhgaDepartment of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

Funding

Japan Society for the Promotion of Science JP23K07334
6 · The paper itself

Abstract

Very-low-birth-weight infants (VLBWIs) are at high risk for neurodevelopmental problems after age 3 years. We investigated the association between the developmental quotient (DQ) of VLBWIs and their growth profiles during 6 years after birth. Participants were VLBWIs born at Kokura Medical Center (the first cohort) and Kyushu University Hospital (the second cohort) between 2012 and 2017. Recorded charts were used to collect growth profiles and developmental quotients (DQ) of the participants until age 6 years. In the first cohort (n = 64), the DQ values at age 6 years were correlated with those at age 3 years. VLBWIs with DQ ≥ 85 at age 6 years had a higher body weight and height at age 3 years than those with DQ < 85. The second cohort (n = 69) validated these findings. A comparative analysis of the two cohorts revealed that the DQ of VLBWIs was dissociated from their growth profiles after age 3 years. Clustering analyses indicated that DQ values at age 3 years predicted better the prognosis of VLBWIs with DQ ≥ 85 at age 6 years than their growth profiles. This study demonstrates that VLBWIs gain divergent profiles in growth, development, and growth-and-development correlation during postnatal 6 years.

Indexed as

Child DevelopmentInfant, Very Low Birth WeightBirth WeightBody WeightChildChild, PreschoolCohort StudiesFemaleHumansInfantInfant, NewbornMaleAgeCorrelationDevelopmentDivergenceGrowthVery-low-birth-weight infants (VLBWIs)

Identifiers

PMID39915669
PMCPMC11802728

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.