Evidence map›Paper›PMID 39915219›Full record

ArticleInternational dental journal2025

Soft Tissue Augmentation by Electrospun Membranes embedded With Nano-Hydroxyapatite: Histologic and Volumetric Analyses.

Yu Zhu, Zuohui Xiao, Yingxin Gu, Qiang Zhi, Zhuoli Huang, Yijie Zhang, Chunan Zhang, Shichong Qiao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International dental journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yu ZhuDepartment of Implant Dentistry, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Oral Diseases, Shanghai, China; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, China.
Zuohui XiaoDepartment of Implant Dentistry, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Oral Diseases, Shanghai, China; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, China.
Yingxin GuDepartment of Implant Dentistry, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Oral Diseases, Shanghai, China; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, China.
Qiang ZhiDepartment of Implant Dentistry, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Oral Diseases, Shanghai, China; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, China.
Zhuoli HuangDepartment of Implant Dentistry, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Oral Diseases, Shanghai, China; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, China.
Yijie ZhangDepartment of Implant Dentistry, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Oral Diseases, Shanghai, China; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, China.
Chunan ZhangDepartment of Implant Dentistry, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Oral Diseases, Shanghai, China; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, China. Electronic address: zcn1114@163.com.
Shichong QiaoDepartment of Implant Dentistry, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Oral Diseases, Shanghai, China; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, China. Electronic address: Shichong83@sjtu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to assess the histologic and volumetric alteration in gingival tissues following grafting with electrospinning collagen membranes blended with nanophased hydroxyapatite (nHA) on the buccal side of canine teeth.

methodsFour adult beagle dogs underwent hemisecting of the mandibular premolars, followed by the extraction of the mesial roots. Soft tissue augmentations were randomly conducted with collagen membranes composed of poly (L-Lactic-co-caprolactone) and porcine fibrinogen (PLCL/F-Fg), PLCL/F-Fg membranes blended with nHA (PLCL/F-Fg/nHA), or a sham-operated control. The animals were sacrificed at 12 weeks post-surgery and received volumetric analyses. Histological examinations at the meantime were carried out at five different depths below the crest (0, 1.5, 2.5, 3.5 and 5.5 mm).

resultsHistological examinations showed a statistically significant increase in buccal gingival thickness between PLCL/F-Fg/20%nHA and PLCL/F-Fg (3.82 ± 1.56mm vs 1.78 ± 0.20mm (at 3.5 mm); 4.23 ± 0.63mm vs 1.80 ± 0.58mm (at 5.5 mm)) as well as between PLCL/F-Fg/20%nHA and PLCL/F-Fg/10%nHA (4.23 ± 0.63mm vs 1.97 ± 0.73mm (at 5.5 mm)). Volumetric analyses showed a statistically significant decrease in volume reduction between PLCL/F-Fg/20%nHA and PLCL/F-Fg (4.46 ± 2.75mm

conclusionPLCL/F-Fg/20%nHA membranes demonstrated effectiveness in the gingival thickness augmentation on the buccal side of canine teeth at 12 weeks postsurgery. The electrospinning collagen membranes blended with nHA rendered an alternative treatment for soft tissue volume augmentations at the pontic site.

Indexed as

DurapatiteGingivaMembranes, ArtificialAnimalsBiocompatible MaterialsCollagenCuspidDogsPolyestersSwineBiocompatible MaterialsCollagenDurapatiteMembranes, ArtificialPolyestersCollagen membranesHistometric analysesNanophased hydroxyapatiteSoft tissue augmentationVolumetric analyses

Identifiers

PMID39915219
PMCPMC12142776

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.