Evidence map›Paper›PMID 39915119›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2025

Collagen Hybridizing Peptide-Based Radiotracers for Molecular Imaging of Collagen Turnover in Pulmonary Fibrosis.

Azmi A Ahmad, Mean Ghim, Gunjan Kukreja, Afarin Neishabouri, Zhengxing Zhang, Jie Li, Mani Salarian, Jakub Toczek, Kiran Gona, Keshvad Hedayatyanfard and 6 more

Abstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Molecular Imaging of Collagen Turnover in Myocardial Infarction.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  2. Article
  3. Review
  4. Molecular Imaging of Collagen Turnover in Myocardial Infarction.bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Around the collagen triple helix: an introduction to studying associated genetic and acquired diseases.Matrix biology : journal of the International Society for Matrix Biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Azmi A AhmadYale Cardiovascular Research Center, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Mean GhimYale Cardiovascular Research Center, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Gunjan KukrejaYale Cardiovascular Research Center, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Afarin NeishabouriYale Cardiovascular Research Center, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Zhengxing ZhangYale Cardiovascular Research Center, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Jie LiYale Cardiovascular Research Center, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Mani SalarianYale Cardiovascular Research Center, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Jakub ToczekYale Cardiovascular Research Center, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Kiran GonaYale Cardiovascular Research Center, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Keshvad HedayatyanfardYale Cardiovascular Research Center, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Tian MorrisonDepartment of Biomedical Engineering and Department of Molecular Pharmaceutics, University of Utah, Salt Lake City, Utah; and.
Jiasheng ZhangYale Cardiovascular Research Center, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Yiyun Henry HuangDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut.
Chi LiuDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut.
S Michael YuDepartment of Biomedical Engineering and Department of Molecular Pharmaceutics, University of Utah, Salt Lake City, Utah; and.
Mehran M SadeghiYale Cardiovascular Research Center, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut; mehran.sadeghi@yale.edu.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Training In Multi-modality Molecular & Translational Cardiovascular ImagingT32HL098069 · NHLBI · YALE UNIVERSITY · PI JAMES S DUNCAN, Georges El Fakhri · 2010 to 2026
$5.2M
PET Imaging of MMP Activation in AAA: First in-Human EvaluationR01AG065917 · NIA · YALE UNIVERSITY · PI GROPLER, ROBERT J., SADEGHI, MEHRAN M · 2020 to 2024
$3.3M
Molecular Imaging of Collagen Turnover in CardiomyopathyR01HL161746 · NHLBI · YALE UNIVERSITY · PI SADEGHI, MEHRAN M · 2022 to 2025
$3.1M
BLRD VA I01 BX006089NCATS NIH HHS UL1 TR001863NHLBI NIH HHS R01 HL161746NHLBI NIH HHS T32 HL098069NIA NIH HHS R01 AG065917
6 · The paper itself

Abstract

Pulmonary fibrosis is a characteristic feature of interstitial lung disease. Current clinical diagnostic methods provide a snapshot of the lung structure without information on disease activity. Collagen hybridizing peptides offer the opportunity to detect collagen remodeling through their hybridization with denatured collagen. Here, we sought to develop a

Indexed as

CollagenMolecular ImagingPeptidesPulmonary FibrosisRadiopharmaceuticalsAnimalsBleomycinMiceRadioactive TracersSingle Photon Emission Computed Tomography Computed TomographyTissue DistributionBleomycinCollagenPeptidesRadioactive TracersRadiopharmaceuticalscollagenmolecular imagingpulmonary fibrosisSPECT/CT

Identifiers

PMID39915119
PMCPMC11876730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.