Evidence map›Paper›PMID 39915040›Full record

ArticleObesity (Silver Spring, Md.)2025

Iron overload is closely associated with metabolic dysfunction-associated fatty liver disease in type 2 diabetes.

Huanjia Qu, Lingling Zhou, Jing Wang, Dong Tang, Qiuling Zhang, Junping Shi

Abstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Huanjia QuDepartment of Endocrinology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Lingling ZhouDepartment of Endocrinology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Jing WangDepartment of Endocrinology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Dong TangDepartment of Radiology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Qiuling ZhangDepartment of Endocrinology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Junping ShiDepartment of Metabolic Disease Center, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.ORCID https://orcid.org/0000-0001-9434-897X

Funding

Medical Science and Technology Project of Zhejiang Province 2023RC234
6 · The paper itself

Abstract

objectiveThe relationship between iron metabolism disturbances and metabolic dysfunction-associated fatty liver disease (MAFLD) remains controversial. This study aimed to investigate the association of iron overload with MAFLD in patients with type 2 diabetes mellitus (T2DM).

methodsThis study included 155 Chinese inpatients with T2DM. MAFLD was diagnosed and grouped using magnetic resonance imaging (MRI). MRI biomarkers such as proton density fat fraction and iron accumulation (

resultsIron metabolism markers, including MRI-

conclusionsMAFLD is associated with significant iron overload in Chinese patients with T2DM. Serum iron, ferritin, total iron-binding capacity, hepcidin, and

Indexed as

Diabetes Mellitus, Type 2Fatty LiverIron OverloadAdultAgedBiomarkersChinaFemaleFerritinsHepcidinsHumansIronLiverMagnetic Resonance ImagingMaleMiddle AgedBiomarkersFerritinsHepcidinsIron

Identifiers

PMID39915040
PMCPMC11897857

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.