Evidence map›Paper›PMID 39914779›Full record

ArticleGastroenterology2025

A Standardized Approach to Performing and Interpreting Functional Lumen Imaging Probe Panometry for Esophageal Motility Disorders: The Dallas Consensus.

Dustin A Carlson, John E Pandolfino, Rena Yadlapati, Marcelo F Vela, Stuart J Spechler, Felice H Schnoll-Sussman, Kristle Lynch, Adriana Lazarescu, Abraham Khan, Philip Katz and 12 more

Abstract readConsensus Statement
In one paragraph

Article in Gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Guideline
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. [Recent Advances in Esophageal Function Testing for Functional Esophageal Disorders].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2026
    Review
  14. Review
  15. Utilization trends for esophageal motility testing in the United States.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Dustin A CarlsonKenneth C. Griffin Esophageal Center of Northwestern Medicine, Division of Gastroenterology and Hepatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. Electronic address: dustin-carlson@northwestern.edu.
John E PandolfinoKenneth C. Griffin Esophageal Center of Northwestern Medicine, Division of Gastroenterology and Hepatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Rena YadlapatiDivision of Gastroenterology, University of California San Diego, La Jolla, California.
Marcelo F VelaDivision of Gastroenterology, Mayo Clinic Arizona, Scottsdale, Arizona.
Stuart J SpechlerDivision of Gastroenterology, Baylor University Medical Center, Dallas, Texas.
Felice H Schnoll-SussmanDepartment of Gastroenterology, Weill Cornell Medical Center, New York, New York.
Kristle LynchDivision of Gastroenterology and Hepatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Adriana LazarescuDivision of Gastroenterology, University of Alberta, Edmonton, Alberta, Canada.
Abraham KhanDivision of Gastroenterology and Hepatology, Department of Medicine, New York University Grossman School of Medicine, New York University Langone Health, New York, New York.
Philip KatzDepartment of Gastroenterology, Weill Cornell Medical Center, New York, New York.
Anand S JainDivision of Digestive Diseases, Department of Internal Medicine, Emory University School of Medicine, Atlanta, Georgia.
C Prakash GyawaliDivision of Gastroenterology, Washington University School of Medicine, St Louis, Missouri.
Milli GuptaDivision of Gastroenterology, University of Calgary, Calgary, Alberta, Canada.
Jose M GarzaGI Care for Kids, Neurogastroenterology and Motility Program, Children's Healthcare of Atlanta, Atlanta, Georgia.
Ronnie FassDigestive Health Center, Division of Gastroenterology and Hepatology, MetroHealth Medical Center, Cleveland, Ohio.
John O ClarkeDivision of Gastroenterology and Hepatology, School of Medicine, Stanford University, Redwood City, California.
Reena V ChokshiDepartment of Medicine, Section of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, Texas.
Joan ChenDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
Karthik RaviDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.
Walter W ChanDivision of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts.
Shahnaz SultanDivision of Gastroenterology, Hepatology, and Nutrition, University of Minnesota, Minneapolis, Minnesota; Veterans Affairs Healthcare System, Minneapolis, Minnesota.
Vani J A KondaDivision of Gastroenterology, Baylor University Medical Center, Dallas, Texas. Electronic address: vanikondaMD@gmail.com.

Funding

The MVP Trial: A Randomized Controlled Trial of Mechanism Guided vs PPI Strategy for Laryngopharyngeal RefluxR01DK139089 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Rena Hiren Yadlapati · 2024 to 2026
$2.0M
Evolution of the Chicago Classification: Bridging Physiology and MechanicsR01DK137775 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Dustin Allan Carlson, JOHN E PANDOLFINO · 2024 to 2026
$1.3M
Mechanism Guided Therapy for Laryngopharyngeal RefluxK23DK125266 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI YADLAPATI, RENA HIREN · 2021 to 2025
$963k
NIDDK NIH HHS K23 DK125266NIDDK NIH HHS R01 DK137775NIDDK NIH HHS R01 DK139089
6 · The paper itself

Abstract

BACKGROUND &

aimsFunctional lumen imaging probe (FLIP) panometry provides assessment of the esophagogastric junction opening and esophageal body contractile activity during an endoscopic procedure and is increasingly being incorporated into comprehensive esophageal motility assessments. The aim of this study was to provide a standardized approach and vocabulary to the procedure and interpretation and update the motility classification scheme.

methodsA working group of 19 FLIP panometry experts convened in a modified Delphi consensus process to produce and assess statements on the FLIP panometry procedure and interpretation. Three rounds of voting were conducted on an agreement scale of 1-9 for appropriateness, followed by face-to-face discussions and an opportunity for revisions of statements. The "percent agreement" was the proportion of votes with score ≥7 indicating level of agreement on appropriateness.

resultsA total of 40 statements were selected for final inclusion in the Dallas Consensus, including FLIP panometry protocol, interpretation of esophagogastric junction opening and contractile response, and motility classification scheme. Key statements included: "FLIP panometry should be interpreted in the context of the clinical presentation, the accompanying EGD [esophagogastroduodenoscopy] findings and other relevant complementary testing" (median response 9.0; 100% agreement). "A major motor disorder is unlikely in the setting of a 'normal' FLIP panometry classification" (median response 9.0; 94% agreement). "Diminished or absent contractile response with reduced esophageal opening (ie, nonspastic obstruction) supports the diagnosis of a disorder of EGJ [esophagogastric junction] outflow" (median response 8.5; 94% agreement).

conclusionsThe standardized approach for performance and interpretation of the Dallas Consensus can facilitate use of FLIP panometry in broad clinical settings.

Indexed as

Endoscopy, Digestive SystemEsophageal Motility DisordersEsophagogastric JunctionDelphi TechniqueHumansManometryMuscle ContractionPredictive Value of TestsAchalasiaDysphagiaEndoscopyImpedance

Identifiers

PMID39914779
PMCPMC12104001

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.