ArticleThe Indian journal of medical research2024
Burkholderia cepacia complex nosocomial outbreaks in India: A scoping review.
Article in The Indian journal of medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Managing Pneumonia Due to Rare Non-Fermenting Gram-Negative Bacteria: Epidemiology, Risk Factors and Therapeutic Strategies.Antibiotics (Basel, Switzerland) · 2026Review
- Decoding Burkholderia Cepacia complex: recA-based species differentiation and antimicrobial susceptibility pattern.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Mixed infection withFrontiers in medicine · 2026Article
- Exploring the efficacy of combination of point-of-use filters and peracetic acid disinfection in reducing total viable counts in final rinse water of endoscopes.Scientific reports · 2025Article
- Acute interstitial pancreatitis withIDCases · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Burkholderia cepacia complex (Bcc) is an opportunistic pathogen that causes severe infections in immunocompromised individuals. It is a common contaminant of medical drugs, solutions and devices used in healthcare setups. This scoping review aimed to assess Bcc outbreaks in Indian hospital settings and address a wide range of sources to improve outbreak management. As per PRISMA-ScR guidelines, electronic databases 'Embase', 'PubMed' and 'Web of Science' were searched from 1993 to September 2024 to identify studies reporting Burkholderia cepacia complex outbreaks across India. The search identified 22 outbreak reports meeting the inclusion criteria. Bacteremia was the most common presentation in twenty studies, followed by acute-onset post-operative endophthalmitis in two studies. In 14 outbreak studies, B. cepacia was the identified species, whereas five studies had Bcc; one study each had B. cenocepacia, B. multivorans and B. contaminans isolated. Most outbreaks were associated with contaminated pharmaceuticals (45.4%) and medical (18.1%) products in contrast to the environment as a source (13.6%). Multi-locus sequence typing (MLST) was employed to study clonality among isolates in six outbreaks. This review highlights that varied medical products and environmental surfaces/objects can harbour Bcc and act as potential sources of Bcc outbreaks in hospitals. Ensuring immediate identification of Bcc from clinical samples, regular sterility checks, thorough epidemiological investigations, and timely infection control and prevention measures are critical to help manage and prevent these outbreaks and the subsequent mortality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.