Evidence map›Paper›PMID 39912988›Full record

ReviewAdvances in therapy2025

Evidence Based Recommendations in Sinonasal Tumors Involving Orbit: Preservation or Exenteration? An IHNSG Guidelines.

Karthik N Rao, Cesare Piazza, Carl Snyderman, Vincent Vander Poorten, M P Sreeram, Primož Strojan, Ehab Hanna, Orlando Guntinas-Lichius, Fernando Lopez, Lauge Hjorth Mikkelsen and 5 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Karthik N RaoDepartment of Head and Neck Surgical Oncology, Sri Shankara Cancer Hospital and Research Center, Sri Shankara Cancer Foundation, Bangalore, India. karthik.nag.rao@gmail.com.ORCID 0000-0002-1420-7366
Cesare PiazzaUnit of Otorhinolaryngology-Head and Neck Surgery, ASST Spedali Civili of Brescia, Brescia, Italy.
Carl SnydermanDepartment of Otolaryngology-Head and Neck Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
Vincent Vander PoortenSection Head and Neck Oncology, Otorhinolaryngology-Head and Neck Surgery and Department of Oncology, University Hospitals Leuven, KU Leuven, Leuven, Belgium.ORCID 0000-0003-1341-829X
M P SreeramDepartment of Head and Neck Surgical Oncology, Sri Shankara Cancer Hospital and Research Center, Sri Shankara Cancer Foundation, Bangalore, India.
Primož StrojanDepartment of Radiation Oncology, Institute of Oncology, Ljubljana, Slovenia.
Ehab HannaDepartment of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Orlando Guntinas-LichiusDepartment of Otorhinolaryngology, Institute of Phoniatry/Pedaudiology, Jena University Hospital, Jena, Germany.
Fernando LopezDepartment of Otolaryngology-Head and Neck Surgery, Hospital Universitario Central de Asturias, University of Oviedo, ISPA, IUOPA, CIBERONC, Oviedo, Spain.
Lauge Hjorth MikkelsenDepartment of Ophthalmology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Carlos SuárezUniversity of Oviedo, Oviedo, Spain.
Akihiro HommaDepartment of Otolaryngology-Head and Neck Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Silvia BabighianDepartment of Ophthalmology, Ospedale Sant'Antonio, Azienda Ospedaliera, Padua, Italy.
Luiz P KowalskiDepartment Otorhinolaryngology-Head and Neck Surgery, Centro de Tratamento e Pesquisa Hospital do Cancer A.C. Camargo, São Paulo, Brazil.
Alfio FerlitoInternational Head and Neck Scientific Group, Padua, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sinonasal tumors with orbital involvement present significant management challenges due to the complex anatomy of the orbital and sinonasal complex and the potential for severe tumor- and treatment-related morbidities. This comprehensive review examines evidence-based decision-making guidelines in the context of treating sinonasal malignancies involving the orbit. We evaluate pre-treatment assessment strategies, discuss the indications for orbital preservation versus its exenteration, explore the role of neo-adjuvant therapies, and analyze reconstruction techniques with ensuing rehabilitation approaches and quality of life. Our review underscores the need for a patient-centered multidisciplinary approach that optimizes treatment outcomes and quality of life for patients suffering from such advanced sinonasal malignancies with orbital involvement.

Indexed as

Nose NeoplasmsOrbital NeoplasmsOrbit EviscerationParanasal Sinus NeoplasmsEvidence-Based MedicineHumansNeoadjuvant TherapyPlastic Surgery ProceduresPractice Guidelines as TopicQuality of LifeEvidence-based decision-makingMultidisciplinary managementOrbital exenterationOrbital preservationSinonasal tumors

Identifiers

PMID39912988

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.