Evidence map›Paper›PMID 39912934›Full record

ReviewArchives of dermatological research2025

Can good sleep quality enhance the benefits of oral collagen supplementation in the prevention of skin aging? A brief report.

Ellen M S Xerfan, Maingredy Rodrigues Souza, Anamaria S Facina, Sergio Tufik, Monica L Andersen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of dermatological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ellen M S XerfanSleep Institute/Associação Fundo de Incentivo a Pesquisa (AFIP), São Paulo, Brazil.
Maingredy Rodrigues SouzaSleep Institute/Associação Fundo de Incentivo a Pesquisa (AFIP), São Paulo, Brazil.
Anamaria S FacinaDepartamento de Dermatologia, Hospital São Paulo, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
Sergio TufikSleep Institute/Associação Fundo de Incentivo a Pesquisa (AFIP), São Paulo, Brazil.
Monica L AndersenSleep Institute/Associação Fundo de Incentivo a Pesquisa (AFIP), São Paulo, Brazil. ml.andersen12@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCollagen is essential to skin structure and integrity, and it is continually degraded with aging due to higher oxidative stress. Sleep deprivation accelerates skin aging and reduces collagen production. Good sleep may be a potential adjuvant to the efficacy of oral supplementation with collagenic peptides for the skin.

objectivesTo summarize clinical benefits to the skin of collagen intake, and consider the role of sleep in its effectiveness.

methodsStudies in the PubMed database that reported the effects of oral administration of collagen peptides were searched; and studies presenting the association of collagen metabolism with sleep.

resultsA total of 1117 articles were initially identified; 66 were reviewed in full. Most involved women at third or fourth decade of life. Daily collagen doses ranged from 1 to 10 g, with intervention periods lasting from 4 to 8 weeks. Consistent improvements in skin elasticity, hydration, and wrinkle reduction were observed, with increase in dermal density and structural proteins. Collagen combined with vitamins, minerals, and antioxidants provided additional benefits, including improved skin radiance and reduced pore size. Studies on sleep and skin indicated that poor sleep can impair skin hydration, increase transepidermic water loss, and reduce elasticity, highlighting the potential role of sleep in maximizing the benefits of collagen supplementation.

conclusionsHydrolyzed collagen supplementation, particularly at 2.5 g/day, has shown benefits for skin after 4 weeks of use. Sleep quality may enhance these effects by supporting immune function and reducing oxidative stress. Further studies are needed on sleep's role in enhancing collagen supplementation benefits.

Indexed as

CollagenDietary SupplementsSkin AgingSleepSleep QualityAdministration, OralAntioxidantsHumansOxidative StressSkinAntioxidantsCollagenCollagenCollagen supplementationExtracellular matrixSkin agingSleepSleep deprivation

Identifiers

PMID39912934

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.