Evidence map›Paper›PMID 39912589›Full record

Trial reportAge and ageing2025

Supporting older people with cognitive impairment during and after hospital stays with intersectoral care management (intersec-CM)-results of a randomised clinical trial.

Melanie Boekholt, Angela Nikelski, Fanny Schumacher-Schoenert, Friederike Kracht, Horst Christian Vollmar, Wolfgang Hoffmann, Stefan Henner Kreisel, Jochen René Thyrian

Registry-linked trialAbstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Age and ageing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03359408 (Supporting Elderly People With Cognitive Impairment During and After Hospital Stays- Intersectoral Care Management [Verbundprojekt Intersec-CM - sektorenübergreifendes Care Management Zur Unterstützung Kognitiv beeinträchtigter Menschen während Und Nach Einem Krankenhausaufenthalt]), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03359408 nacompletednot on this map

Supporting Elderly People With Cognitive Impairment During and After Hospital Stays- Intersectoral Care Management [Verbundprojekt Intersec-CM - sektorenübergreifendes Care Management Zur Unterstützung Kognitiv beeinträchtigter Menschen während Und Nach Einem Krankenhausaufenthalt]

TypeinterventionalSponsorGerman Center for Neurodegenerative Diseases (DZNE)Ran2018 to 2022Enrolled401ConditionsDementia, Cognitive Impairment, Neurodegenerative DiseasesArmsDementia Care Management (DCM)
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Melanie BoekholtGerman Centre for Neurodegenerative Diseases, site Rostock/Greifswald, Ellernholzstraße 1-2, Greifswald 17489, Germany.ORCID 0000-0002-0576-0012
Angela NikelskiDepartment of Psychiatry and Psychotherapy Bethel, Division of Geriatric Psychiatry, Evangelisches Klinikum Bethel gGmbH, Bielefeld, Nordrhein-Westfalen, Germany.
Fanny Schumacher-SchoenertGerman Centre for Neurodegenerative Diseases, site Rostock/Greifswald, Ellernholzstraße 1-2, Greifswald 17489, Germany.
Friederike KrachtGerman Centre for Neurodegenerative Diseases, site Rostock/Greifswald, Ellernholzstraße 1-2, Greifswald 17489, Germany.
Horst Christian VollmarRuhr University Bochum, Bochum, Nordrhein-Westfalen, Germany.
Wolfgang HoffmannGerman Centre for Neurodegenerative Diseases, site Rostock/Greifswald, Ellernholzstraße 1-2, Greifswald 17489, Germany.
Stefan Henner KreiselDepartment of Psychiatry and Psychotherapy Bethel, Division of Geriatric Psychiatry, Evangelisches Klinikum Bethel gGmbH, Bielefeld, Nordrhein-Westfalen, Germany.ORCID 0000-0001-7623-3423
Jochen René ThyrianGerman Centre for Neurodegenerative Diseases, site Rostock/Greifswald, Ellernholzstraße 1-2, Greifswald 17489, Germany.

Funding

Evangelisches Klinikum Bethel, Division of Geriatric Psychiatry, Bielefeld 01GL1701BGerman Center for Neurodegenerative Diseases 01GL1701AGerman Federal Ministry of Education and ResearchInstitute of Community Medicine, Department of Epidemiology and Community Health 01GL1701DInstitute of General Practice and Family Medicine 01GL1701C
6 · The paper itself

Abstract

backgroundThe transition from hospital to primary care is a risk factor for negative health outcomes in people with cognitive impairment.

objectiveTo test the effectiveness of intersectoral care management during the transition from hospital to primary care on repeated admission to hospital, functionality and institutionalisation in people with cognitive impairment.

designLongitudinal multisite randomised controlled trial with two arms (care as usual and intersectoral care management) and two follow-ups 3 and 12 months after discharge.

settingThree hospitals in two different primary care regions in Germany. SUBJECTS: n = 401 people with cognitive impairment: community-dwelling, age 70+. Randomised into control (n = 192) or intervention (n = 209).

methodsPrimary outcomes for the study after 3 months: admission to hospital, physical and instrumental functionality. Primary outcome after 12 months: institutionalisation, physical and instrumental functionality. Secondary outcomes: health-related quality of life, depressive symptoms, cognitive status and frailty. Statistical analyses include descriptive analyses as well as univariate and multivariate regression models for all outcomes.

resultsThere was no statistically significant effect of the intervention on hospital admission and activities of daily living after 3 months, as well as on institutionalisation and activities of daily living after 12 months. There were significantly fewer participants in the intervention group readmitted to the hospital 12 months after discharge.Analyses show a significant effect on health-related quality of life 3 months and 12 months after discharge. Depressive symptoms were significantly less likely in the intervention group 3 months after discharge. No effects on cognition or frailty.

conclusionIntersectoral care management supports people with cognitive impairment during discharge and transition. Even though we were not able to show an impact of the intervention on the chosen primary outcomes everyday functionality and institutionalisation, the effects on health-related quality of life, hospital admission rate and mental health are solid indicators for an improved individual situation.

trial registrationClinicalTrials.gov, NCT03359408; https://clinicaltrials.gov/ct2/show/NCT03359408.

Indexed as

Cognitive DysfunctionActivities of Daily LivingAgedAged, 80 and overAge FactorsCognitionDepressionFemaleFunctional StatusGeriatric AssessmentGermanyHospitalizationHumansInstitutionalizationLongitudinal StudiesMalecognitive impairmentdementia care managementGermanyhospital dischargeolder peoplerandomised controlled trial

Identifiers

PMID39912589
PMCPMC11800143

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.