ArticleNeurology. Genetics2024
A 3'UTR Insertion Is a Candidate Causal Variant at the
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Article in Neurology. Genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.
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16citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed.
- TMEM106B is a selective modulator of TDP-43 pathology in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Clinical Associations of Cerebrospinal Fluid TMEM106B in Familial and Sporadic Frontotemporal Dementia.JAMA neurology · 2026Article
- Neurodegeneration risk variants promote lysosomal TMEM106B fibril accumulation.bioRxiv : the preprint server for biology · 2026Article
- Granulin loss and TMEM106B risk converge on lysosomal C-terminal fragment pathology in frontotemporal dementia.bioRxiv : the preprint server for biology · 2026Article
- Genetic correlation analysis identifies TMEM106B, ACE, and ERC2 as genetic loci shared between Alzheimer's disease and primary psychiatric disorders.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- The Impact of Structural Variation on Alzheimer's Disease in the Alzheimer's Disease Sequencing Project.Research square · 2026Article
- TDP-43 nuclear loss in FTD/ALS causes widespread alternative polyadenylation changes.Nature neuroscience · 2025Article
- Long-read genome sequencing and multi-omics in aging and neurodegeneration.medRxiv : the preprint server for health sciences · 2025Article
- The role of endolysosomal progranulin and TMEM106B in neurodegenerative diseases.Molecular neurodegeneration · 2025Review
- Structural variation detection and association analysis of whole-genome-sequence data from 16,543 Alzheimer's disease sequencing project subjects.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Integration of transcriptomics and long-read genomics prioritizes structural variants in rare disease.Genome research · 2025Article
- Structural variants linked to Alzheimer's disease and other common age-related clinical and neuropathologic traits.Genome medicine · 2025Article
- Structural variants linked to Alzheimer's Disease and other common age-related clinical and neuropathologic traits.medRxiv : the preprint server for health sciences · 2024Article
- Correction to Preprint Server Information.Neurology. Genetics · 2024Article
- Integration of transcriptomics and long-read genomics prioritizes structural variants in rare disease.medRxiv : the preprint server for health sciences · 2024Article
- A 3'UTR Insertion Is a Candidate Causal Variant at theNeurology. Genetics · 2024Article
Corrections and comments
- Erratum issued
- Update of
Authors and funding
18 authors.
Augustine ChemparathyFrom the Department of Neurology and Neurological Sciences (A.C., Y.L.G., N.K., L.T., M.B., I.S., V.W.H., T.W.-C., M.D.G.); Quantitative Sciences Unit (Y.L.G.), Department of Medicine; Department of Genetics (Y.Z., J.G., T.D.J., A.D.G., E.A.); Division of Cardiology (J.G., E.A.), Department of Medicine, Stanford University School of Medicine, CA; Neurogenomics and Informatics Center (C.Y., C.C.), Washington University School of Medicine, St. Louis, MO; Wu Tsai Neurosciences Institute (A.D.W., E.M.); Department of Psychology (A.D.W., E.M.); and Department of Epidemiology and Population Health (V.W.H.), Stanford University, CA.ORCID https://orcid.org/0000-0003-3222-1724
Yann Le GuenFrom the Department of Neurology and Neurological Sciences (A.C., Y.L.G., N.K., L.T., M.B., I.S., V.W.H., T.W.-C., M.D.G.); Quantitative Sciences Unit (Y.L.G.), Department of Medicine; Department of Genetics (Y.Z., J.G., T.D.J., A.D.G., E.A.); Division of Cardiology (J.G., E.A.), Department of Medicine, Stanford University School of Medicine, CA; Neurogenomics and Informatics Center (C.Y., C.C.), Washington University School of Medicine, St. Louis, MO; Wu Tsai Neurosciences Institute (A.D.W., E.M.); Department of Psychology (A.D.W., E.M.); and Department of Epidemiology and Population Health (V.W.H.), Stanford University, CA.ORCID https://orcid.org/0000-0001-6649-8364
Yi ZengFrom the Department of Neurology and Neurological Sciences (A.C., Y.L.G., N.K., L.T., M.B., I.S., V.W.H., T.W.-C., M.D.G.); Quantitative Sciences Unit (Y.L.G.), Department of Medicine; Department of Genetics (Y.Z., J.G., T.D.J., A.D.G., E.A.); Division of Cardiology (J.G., E.A.), Department of Medicine, Stanford University School of Medicine, CA; Neurogenomics and Informatics Center (C.Y., C.C.), Washington University School of Medicine, St. Louis, MO; Wu Tsai Neurosciences Institute (A.D.W., E.M.); Department of Psychology (A.D.W., E.M.); and Department of Epidemiology and Population Health (V.W.H.), Stanford University, CA.ORCID https://orcid.org/0000-0001-8306-8323
John GorzynskiFrom the Department of Neurology and Neurological Sciences (A.C., Y.L.G., N.K., L.T., M.B., I.S., V.W.H., T.W.-C., M.D.G.); Quantitative Sciences Unit (Y.L.G.), Department of Medicine; Department of Genetics (Y.Z., J.G., T.D.J., A.D.G., E.A.); Division of Cardiology (J.G., E.A.), Department of Medicine, Stanford University School of Medicine, CA; Neurogenomics and Informatics Center (C.Y., C.C.), Washington University School of Medicine, St. Louis, MO; Wu Tsai Neurosciences Institute (A.D.W., E.M.); Department of Psychology (A.D.W., E.M.); and Department of Epidemiology and Population Health (V.W.H.), Stanford University, CA.ORCID https://orcid.org/0000-0002-9034-9016
Tanner D JensenFrom the Department of Neurology and Neurological Sciences (A.C., Y.L.G., N.K., L.T., M.B., I.S., V.W.H., T.W.-C., M.D.G.); Quantitative Sciences Unit (Y.L.G.), Department of Medicine; Department of Genetics (Y.Z., J.G., T.D.J., A.D.G., E.A.); Division of Cardiology (J.G., E.A.), Department of Medicine, Stanford University School of Medicine, CA; Neurogenomics and Informatics Center (C.Y., C.C.), Washington University School of Medicine, St. Louis, MO; Wu Tsai Neurosciences Institute (A.D.W., E.M.); Department of Psychology (A.D.W., E.M.); and Department of Epidemiology and Population Health (V.W.H.), Stanford University, CA.ORCID https://orcid.org/0000-0002-1873-8607
Chengran YangFrom the Department of Neurology and Neurological Sciences (A.C., Y.L.G., N.K., L.T., M.B., I.S., V.W.H., T.W.-C., M.D.G.); Quantitative Sciences Unit (Y.L.G.), Department of Medicine; Department of Genetics (Y.Z., J.G., T.D.J., A.D.G., E.A.); Division of Cardiology (J.G., E.A.), Department of Medicine, Stanford University School of Medicine, CA; Neurogenomics and Informatics Center (C.Y., C.C.), Washington University School of Medicine, St. Louis, MO; Wu Tsai Neurosciences Institute (A.D.W., E.M.); Department of Psychology (A.D.W., E.M.); and Department of Epidemiology and Population Health (V.W.H.), Stanford University, CA.ORCID https://orcid.org/0000-0003-4577-5590
Nandita KasireddyFrom the Department of Neurology and Neurological Sciences (A.C., Y.L.G., N.K., L.T., M.B., I.S., V.W.H., T.W.-C., M.D.G.); Quantitative Sciences Unit (Y.L.G.), Department of Medicine; Department of Genetics (Y.Z., J.G., T.D.J., A.D.G., E.A.); Division of Cardiology (J.G., E.A.), Department of Medicine, Stanford University School of Medicine, CA; Neurogenomics and Informatics Center (C.Y., C.C.), Washington University School of Medicine, St. Louis, MO; Wu Tsai Neurosciences Institute (A.D.W., E.M.); Department of Psychology (A.D.W., E.M.); and Department of Epidemiology and Population Health (V.W.H.), Stanford University, CA.ORCID https://orcid.org/0000-0001-6594-2814
Lia TalozziFrom the Department of Neurology and Neurological Sciences (A.C., Y.L.G., N.K., L.T., M.B., I.S., V.W.H., T.W.-C., M.D.G.); Quantitative Sciences Unit (Y.L.G.), Department of Medicine; Department of Genetics (Y.Z., J.G., T.D.J., A.D.G., E.A.); Division of Cardiology (J.G., E.A.), Department of Medicine, Stanford University School of Medicine, CA; Neurogenomics and Informatics Center (C.Y., C.C.), Washington University School of Medicine, St. Louis, MO; Wu Tsai Neurosciences Institute (A.D.W., E.M.); Department of Psychology (A.D.W., E.M.); and Department of Epidemiology and Population Health (V.W.H.), Stanford University, CA.ORCID https://orcid.org/0000-0003-1827-0407
Michael BelloyFrom the Department of Neurology and Neurological Sciences (A.C., Y.L.G., N.K., L.T., M.B., I.S., V.W.H., T.W.-C., M.D.G.); Quantitative Sciences Unit (Y.L.G.), Department of Medicine; Department of Genetics (Y.Z., J.G., T.D.J., A.D.G., E.A.); Division of Cardiology (J.G., E.A.), Department of Medicine, Stanford University School of Medicine, CA; Neurogenomics and Informatics Center (C.Y., C.C.), Washington University School of Medicine, St. Louis, MO; Wu Tsai Neurosciences Institute (A.D.W., E.M.); Department of Psychology (A.D.W., E.M.); and Department of Epidemiology and Population Health (V.W.H.), Stanford University, CA.ORCID https://orcid.org/0000-0001-7748-9033
Ilaria StewartFrom the Department of Neurology and Neurological Sciences (A.C., Y.L.G., N.K., L.T., M.B., I.S., V.W.H., T.W.-C., M.D.G.); Quantitative Sciences Unit (Y.L.G.), Department of Medicine; Department of Genetics (Y.Z., J.G., T.D.J., A.D.G., E.A.); Division of Cardiology (J.G., E.A.), Department of Medicine, Stanford University School of Medicine, CA; Neurogenomics and Informatics Center (C.Y., C.C.), Washington University School of Medicine, St. Louis, MO; Wu Tsai Neurosciences Institute (A.D.W., E.M.); Department of Psychology (A.D.W., E.M.); and Department of Epidemiology and Population Health (V.W.H.), Stanford University, CA.ORCID https://orcid.org/0000-0002-8655-9387
Aaron D GitlerFrom the Department of Neurology and Neurological Sciences (A.C., Y.L.G., N.K., L.T., M.B., I.S., V.W.H., T.W.-C., M.D.G.); Quantitative Sciences Unit (Y.L.G.), Department of Medicine; Department of Genetics (Y.Z., J.G., T.D.J., A.D.G., E.A.); Division of Cardiology (J.G., E.A.), Department of Medicine, Stanford University School of Medicine, CA; Neurogenomics and Informatics Center (C.Y., C.C.), Washington University School of Medicine, St. Louis, MO; Wu Tsai Neurosciences Institute (A.D.W., E.M.); Department of Psychology (A.D.W., E.M.); and Department of Epidemiology and Population Health (V.W.H.), Stanford University, CA.ORCID https://orcid.org/0000-0001-8603-1526
Anthony D WagnerFrom the Department of Neurology and Neurological Sciences (A.C., Y.L.G., N.K., L.T., M.B., I.S., V.W.H., T.W.-C., M.D.G.); Quantitative Sciences Unit (Y.L.G.), Department of Medicine; Department of Genetics (Y.Z., J.G., T.D.J., A.D.G., E.A.); Division of Cardiology (J.G., E.A.), Department of Medicine, Stanford University School of Medicine, CA; Neurogenomics and Informatics Center (C.Y., C.C.), Washington University School of Medicine, St. Louis, MO; Wu Tsai Neurosciences Institute (A.D.W., E.M.); Department of Psychology (A.D.W., E.M.); and Department of Epidemiology and Population Health (V.W.H.), Stanford University, CA.ORCID https://orcid.org/0000-0003-0624-4543
Elizabeth MorminoFrom the Department of Neurology and Neurological Sciences (A.C., Y.L.G., N.K., L.T., M.B., I.S., V.W.H., T.W.-C., M.D.G.); Quantitative Sciences Unit (Y.L.G.), Department of Medicine; Department of Genetics (Y.Z., J.G., T.D.J., A.D.G., E.A.); Division of Cardiology (J.G., E.A.), Department of Medicine, Stanford University School of Medicine, CA; Neurogenomics and Informatics Center (C.Y., C.C.), Washington University School of Medicine, St. Louis, MO; Wu Tsai Neurosciences Institute (A.D.W., E.M.); Department of Psychology (A.D.W., E.M.); and Department of Epidemiology and Population Health (V.W.H.), Stanford University, CA.ORCID https://orcid.org/0000-0002-4542-6537
Victor W HendersonFrom the Department of Neurology and Neurological Sciences (A.C., Y.L.G., N.K., L.T., M.B., I.S., V.W.H., T.W.-C., M.D.G.); Quantitative Sciences Unit (Y.L.G.), Department of Medicine; Department of Genetics (Y.Z., J.G., T.D.J., A.D.G., E.A.); Division of Cardiology (J.G., E.A.), Department of Medicine, Stanford University School of Medicine, CA; Neurogenomics and Informatics Center (C.Y., C.C.), Washington University School of Medicine, St. Louis, MO; Wu Tsai Neurosciences Institute (A.D.W., E.M.); Department of Psychology (A.D.W., E.M.); and Department of Epidemiology and Population Health (V.W.H.), Stanford University, CA.ORCID https://orcid.org/0000-0003-1198-9240
Tony Wyss-CorayFrom the Department of Neurology and Neurological Sciences (A.C., Y.L.G., N.K., L.T., M.B., I.S., V.W.H., T.W.-C., M.D.G.); Quantitative Sciences Unit (Y.L.G.), Department of Medicine; Department of Genetics (Y.Z., J.G., T.D.J., A.D.G., E.A.); Division of Cardiology (J.G., E.A.), Department of Medicine, Stanford University School of Medicine, CA; Neurogenomics and Informatics Center (C.Y., C.C.), Washington University School of Medicine, St. Louis, MO; Wu Tsai Neurosciences Institute (A.D.W., E.M.); Department of Psychology (A.D.W., E.M.); and Department of Epidemiology and Population Health (V.W.H.), Stanford University, CA.ORCID https://orcid.org/0000-0001-5893-0831
Euan AshleyFrom the Department of Neurology and Neurological Sciences (A.C., Y.L.G., N.K., L.T., M.B., I.S., V.W.H., T.W.-C., M.D.G.); Quantitative Sciences Unit (Y.L.G.), Department of Medicine; Department of Genetics (Y.Z., J.G., T.D.J., A.D.G., E.A.); Division of Cardiology (J.G., E.A.), Department of Medicine, Stanford University School of Medicine, CA; Neurogenomics and Informatics Center (C.Y., C.C.), Washington University School of Medicine, St. Louis, MO; Wu Tsai Neurosciences Institute (A.D.W., E.M.); Department of Psychology (A.D.W., E.M.); and Department of Epidemiology and Population Health (V.W.H.), Stanford University, CA.ORCID https://orcid.org/0000-0001-9418-9577
Carlos CruchagaFrom the Department of Neurology and Neurological Sciences (A.C., Y.L.G., N.K., L.T., M.B., I.S., V.W.H., T.W.-C., M.D.G.); Quantitative Sciences Unit (Y.L.G.), Department of Medicine; Department of Genetics (Y.Z., J.G., T.D.J., A.D.G., E.A.); Division of Cardiology (J.G., E.A.), Department of Medicine, Stanford University School of Medicine, CA; Neurogenomics and Informatics Center (C.Y., C.C.), Washington University School of Medicine, St. Louis, MO; Wu Tsai Neurosciences Institute (A.D.W., E.M.); Department of Psychology (A.D.W., E.M.); and Department of Epidemiology and Population Health (V.W.H.), Stanford University, CA.ORCID https://orcid.org/0000-0002-0276-2899
Michael D GreiciusFrom the Department of Neurology and Neurological Sciences (A.C., Y.L.G., N.K., L.T., M.B., I.S., V.W.H., T.W.-C., M.D.G.); Quantitative Sciences Unit (Y.L.G.), Department of Medicine; Department of Genetics (Y.Z., J.G., T.D.J., A.D.G., E.A.); Division of Cardiology (J.G., E.A.), Department of Medicine, Stanford University School of Medicine, CA; Neurogenomics and Informatics Center (C.Y., C.C.), Washington University School of Medicine, St. Louis, MO; Wu Tsai Neurosciences Institute (A.D.W., E.M.); Department of Psychology (A.D.W., E.M.); and Department of Epidemiology and Population Health (V.W.H.), Stanford University, CA.ORCID https://orcid.org/0000-0002-5462-9037
Funding
Hippocampal-dependent memory decline in aging and early Alzheimer's diseaseR01AG074339 · NIA · STANFORD UNIVERSITY · PI ELIZABETH MORMINO · 2022 to 2026
$6.0MIlluminating the APOE Locus with Long-Read Sequencing and Targeted GenomicsR35AG072290 · NIA · STANFORD UNIVERSITY · PI GREICIUS, MICHAEL D · 2021 to 2025
$4.6MNIA NIH HHS R01 AG074339NIA NIH HHS R35 AG072290
Abstract
Background and Objectives: Single-nucleotide variants near Methods: An exploratory analysis identified structural variants on neurodegeneration-related genes. Subsequent analyses focused on an Results: The primary analysis included 432 participants (52.5% female, age range 45-92 years). We identified a 316 bp Discussion: We identified a novel
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