ArticleJournal of inflammation research2025
Significance of the Lesion-Pleura Relationship in Differentiating Peripheral Inflammatory Lesions and Lung Cancers.
Article in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: To determine the significance of lesion-pleura relationship in differentiating peripheral inflammatory lesions (PILs) and peripheral lung cancers (PLCs). Patients and Methods: From January 2017 to April 2022, a total of 743 patients with 501 PLCs and 292 PILs (≥1.5 cm) were retrospectively enrolled. The patients' clinical characteristics and CT features of lesions in these two groups were analyzed and compared, and the impact of the lesion-pleura relationship (broad or narrow basement and distance between lesion and pleura) on differentiation was specifically assessed. Results: Lesions attached to pleura were more frequent in PILs (188, 64.4%) than in PLCs (244, 48.7%) ( Conclusion: When differentiating peripheral lesions (≥1.5 cm), it is crucial to consider the basement-to-pleura and lesion-pleura distance besides patients' clinical characteristics, laboratory parameters and morphological features.
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