Evidence map›Paper›PMID 39911868›Full record

ArticleFrontiers in medicine2025

Hypomagnesemia, insulin secretion and action in patients without diabetes, 1 year after kidney transplantation.

Rasmus K Carlsen, Anders Åsberg, My Svensson, Kåre I Birkeland, Hanne S Jørgensen, Iain Bressendorff, Hanne L Gulseth, Karsten Midtvedt, Espen Nordheim, Trond G Jenssen

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Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Rasmus K CarlsenDepartment of Transplantation Medicine, Oslo University Hospital and University of Oslo, Oslo, Norway.
Anders ÅsbergDepartment of Transplantation Medicine, Oslo University Hospital and University of Oslo, Oslo, Norway.
My SvenssonDepartment of Nephrology, Akershus University Hospital, Lørenskog, Norway.
Kåre I BirkelandDepartment of Transplantation Medicine, Oslo University Hospital and University of Oslo, Oslo, Norway.
Hanne S JørgensenDepartment of Kidney Disease, Aarhus University Hospital, Aarhus, Denmark.
Iain BressendorffDepartment of Nephrology, Herlev and Gentofte Hospital, Herlev, Denmark.
Hanne L GulsethInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.
Karsten MidtvedtDepartment of Transplantation Medicine, Oslo University Hospital and University of Oslo, Oslo, Norway.
Espen NordheimDepartment of Transplantation Medicine, Oslo University Hospital and University of Oslo, Oslo, Norway.
Trond G JenssenDepartment of Transplantation Medicine, Oslo University Hospital and University of Oslo, Oslo, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Hypomagnesemia after kidney transplantation has been reported as a potential risk factor for development of post-transplant diabetes mellitus. Methods: In kidney transplant recipients undergoing an oral glucose tolerance test during one-year surveillance follow-up we estimated insulin sensitivity with the Matsuda index, a modified Stumvoll index, and HOMA-2 Results: We included 208 patients (62% men, median age 51 years). Patients in the lowest compared to the highest magnesium tertile had higher measured GFR (mean 59 vs. 49 mL/min, Conclusion: In kidney transplant recipients with lower compared to normal plasma magnesium levels we found a higher fasting plasma glucose but no differences in insulin sensitivity indexes nor dynamic insulin measurements.

Indexed as

hypomagnesemiainsulin actioninsulin secretionkidney transplantationoral glucose tolerance testpost-transplant diabetes mellitus

Identifiers

PMID39911868
PMCPMC11797832

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