Evidence map›Paper›PMID 39911860›Full record

ArticleFrontiers in medicine2025

Risk factors for new vertebral fractures after percutaneous vertebroplasty or percutaneous kyphoplasty in the treatment of osteoporotic vertebral compression fractures.

Wencheng Yang, Kaiwei Zou, Xuping Lin, Yanfang Yang, Tianpei Chen, Xiuming Wu, Xiaomeng Wang, Qingjun Liu, Chunhui Huang, Wanhan Su

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Influence of Loading Modalities on Remodeling-Based Bone Formation in Severe OVCF Patients.International journal for numerical methods in biomedical engineering · 2026
    Article
  3. Review
  4. Development and validation of machine learning models for predicting the risk of refracture after percutaneous kyphoplasty in OVCF patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wencheng Yang *Department of Spine Surgery, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Kaiwei Zou *Department of Spine Surgery, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Xuping Lin *Department of Spine Surgery, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Yanfang YangDepartment of Cardiology, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, Fujian, China.
Tianpei ChenDepartment of Spine Surgery, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Xiuming WuDepartment of Spine Surgery, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Xiaomeng WangDepartment of Spine Surgery, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Qingjun LiuDepartment of Orthopaedic, Affiliated Dongnan Hospital of Xiamen University, Zhangzhou, China.
Chunhui HuangDepartment of Spine Surgery, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Wanhan SuDepartment of Spine Surgery, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Object: This study aims to conduct a prospective analysis of patients with osteoporotic vertebral compression fractures (OVCF) who underwent percutaneous vertebroplasty (PVP) or percutaneous kyphoplasty (PKP), and further analyze the risk factors for new vertebral fracture following treatment. Methods: A prospective study was conducted from November 2020 to March 2022 at the First Hospital of Longyan City to select patients with OVCF who underwent treatment in the Department of Spinal Surgery. Data collection during the follow-up period focused on various factors that could potentially be associated with new vertebral fractures after PVP/PKP procedures. Patients were divided into two groups based on whether they experienced new vertebral fractures within two years after discharge: the new fracture group ( Results: All cases were followed up for 12 to 24 months, with an average of 14.7 months. Differential analysis revealed that age, diabetes, hemoglobin (HB), total protein (TP), serum albumin (ALB), b-C-terminal telopeptide of type I collage (β-CTX), 25-hydroxyvitamin D (25-OH-D3), number of fractured vertebrae, bone mineral density (BMD), regular exercise after discharge, anti-osteoporosis treatment after discharge, cross-sectional area (CSA), and fatty degeneration ratio (FDR) were associated with new vertebral fractures (all Conclusion: Patients with osteoporosis fractures who are older, have poor glycemic control, lower bone mineral density, lower levels of 25-OH-D3, weaker paraspinal muscles, and higher fat infiltration are at increased risk of new vertebral fractures after undergoing PKP/PVP. On the other hand, maintaining regular physical activity and adhering to osteoporosis treatment can help prevent new vertebral fractures.

Indexed as

new vertebral fracturesosteoporotic vertebral compression fracturespercutaneous kyphoplastypercutaneous vertebroplastyrisk factorssenior citizen

Identifiers

PMID39911860
PMCPMC11794209

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.