ArticleFrontiers in pediatrics2024
Critical appraisal of diagnostic laboratory tests in the evaluation of central precocious puberty.
Article in Frontiers in pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Interpreting the GnRH stimulation test in girls with central precocious puberty: the role of age and body mass index.Journal of endocrinological investigation · 2026Article
- Obesity and insulin resistance trigger the early onset of adolescent-like sexually dimorphic metabotypes in middle childhood.Cardiovascular diabetology · 2026Article
- Development and evaluation of a predictive model for central precocious puberty in girls.Translational pediatrics · 2026Article
- The Diagnostic Utility of the Triptorelin Stimulation Test Compared to the Standard Gonadotropin-Releasing Hormone Stimulation Test in Children with Idiopathic Central Precocious Puberty.Diseases (Basel, Switzerland) · 2025Article
- Predictive Modeling of Central Precocious Puberty Using IGF-1 and IGFBP-3 Standard Deviation Scores.Diagnostics (Basel, Switzerland) · 2025Article
- Genetic, neuropeptidergic, and cardiometabolic interplay in female central precocious puberty.Cardiovascular endocrinology & metabolism · 2025Review
- Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pubertal onset is characterized by reactivation of the hypothalamic-pituitary-gonadal axis resulting in pulsatile gonadotropin secretion and subsequent sex steroid production. Accurate measurements of the gonadotropins and sex steroids are essential to ensure timely diagnosis of precocious puberty, so as to determine optimal management. This review summarizes the available laboratory testing for the diagnosis of puberty, discussing the different assays used while reviewing the limitations of such testing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.