Evidence map›Paper›PMID 39911715›Full record

ReviewFrontiers in microbiology2024

Deep learning in microbiome analysis: a comprehensive review of neural network models.

Piotr Przymus, Krzysztof Rykaczewski, Adrián Martín-Segura, Jaak Truu, Enrique Carrillo De Santa Pau, Mikhail Kolev, Irina Naskinova, Aleksandra Gruca, Alexia Sampri, Marcus Frohme and 1 more

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Piotr Przymus *Faculty of Mathematics and Computer Science, Nicolaus Copernicus University in Toruń, Toruń, Pomeranian, Poland.
Krzysztof Rykaczewski *Faculty of Mathematics and Computer Science, Nicolaus Copernicus University in Toruń, Toruń, Pomeranian, Poland.
Adrián Martín-Segura *Computational Biology Group, IMDEA Food Institute, Madrid, Spain.
Jaak Truu *Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.
Enrique Carrillo De Santa PauComputational Biology Group, IMDEA Food Institute, Madrid, Spain.
Mikhail KolevDepartment of Mathematics, University of Architecture, Civil Engineering and Geodesy, Sofia, Bulgaria.
Irina NaskinovaDepartment of Mathematics, University of Architecture, Civil Engineering and Geodesy, Sofia, Bulgaria.
Aleksandra GrucaDepartment of Computer Networks and Systems, Silesian University of Technology, Gliwice, Poland.
Alexia SampriBritish Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
Marcus FrohmeMolecular Biotechnology and Functional Genomics, Technical University of Applied Sciences Wildau, Wildau, Brandenburg, Germany.
Alina NechyporenkoMolecular Biotechnology and Functional Genomics, Technical University of Applied Sciences Wildau, Wildau, Brandenburg, Germany.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Microbiome research, the study of microbial communities in diverse environments, has seen significant advances due to the integration of deep learning (DL) methods. These computational techniques have become essential for addressing the inherent complexity and high-dimensionality of microbiome data, which consist of different types of omics datasets. Deep learning algorithms have shown remarkable capabilities in pattern recognition, feature extraction, and predictive modeling, enabling researchers to uncover hidden relationships within microbial ecosystems. By automating the detection of functional genes, microbial interactions, and host-microbiome dynamics, DL methods offer unprecedented precision in understanding microbiome composition and its impact on health, disease, and the environment. However, despite their potential, deep learning approaches face significant challenges in microbiome research. Additionally, the biological variability in microbiome datasets requires tailored approaches to ensure robust and generalizable outcomes. As microbiome research continues to generate vast and complex datasets, addressing these challenges will be crucial for advancing microbiological insights and translating them into practical applications with DL. This review provides an overview of different deep learning models in microbiome research, discussing their strengths, practical uses, and implications for future studies. We examine how these models are being applied to solve key problems and highlight potential pathways to overcome current limitations, emphasizing the transformative impact DL could have on the field moving forward.

Indexed as

classificationclusteringdeep learningmicrobiomenatural language processing

Identifiers

PMID39911715
PMCPMC11794229

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.