ArticleFrontiers in medicine2024
Ten-year outcomes of repeat keratoplasty for optical indications.
Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Indications and long-term outcomes of repeat optical penetrating keratoplasty.Indian journal of ophthalmology · 2026Article
- Outcomes of Therapeutic and Tectonic Penetrating Keratoplasty for Advanced Corneal Disease.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Outcomes of Synthetic Corneal Endothelial Implant in Patients with Corneal Oedema with or without Prior Endothelial Keratoplasty: A Case Series.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: To analyze the clinical outcomes of repeat keratoplasties following a failed primary optical keratoplasty in an Asian population. Methods: In this prospective cohort study, clinical data of consecutive patients who had repeat keratoplasty at Singapore National Eye Centre from 2007 to 2020 were recorded from our ongoing Singapore Corneal Transplant Registry. Results: A total of 284 first regrafts (181 Descemet stripping automated endothelial keratoplasty (EK), 63 penetrating keratoplasty (PK), 21 Descemet membrane endothelial keratoplasty, and 19 deep anterior lamellar keratoplasty (DALK)) were analyzed. Graft rejection (38.4%) and late endothelial failure (15.8%) were the main causes of initial graft failure. PK/EK and EK/EK had better one-year postoperative best corrected visual acuity compared to PK/PK ( Conclusion: Performing EK for failed optical PK or EK significantly improved regraft survival compared to repeat PK. Regrafts performed for failed initial DALK grafts did well regardless of type.
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