Evidence map›Paper›PMID 39911606›Full record

ArticleFrontiers in medical technology2025

Beyond sensitivity: what are the enabling opportunities of OPM-MEG?

Timothy P L Roberts, Charlotte Birnbaum, Luke Bloy, William Gaetz

Abstract read
In one paragraph

Article in Frontiers in medical technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Timothy P L RobertsDepartment of Radiology, Program in Advanced Imaging Research and Lurie Family Foundations MEG Imaging Center, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Charlotte BirnbaumDepartment of Radiology, Program in Advanced Imaging Research and Lurie Family Foundations MEG Imaging Center, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Luke BloyDepartment of Radiology, Program in Advanced Imaging Research and Lurie Family Foundations MEG Imaging Center, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
William GaetzDepartment of Radiology, Program in Advanced Imaging Research and Lurie Family Foundations MEG Imaging Center, Children's Hospital of Philadelphia, Philadelphia, PA, United States.

Funding

The Intellectual and Developmental Disabilities Research Center (IDDRC) at CHOP/PennP50HD105354 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI ERIC D MARSH, ROBERT Thomas SCHULTZ · 2021 to 2026
$9.2M
NICHD NIH HHS P50 HD105354
6 · The paper itself

Abstract

While optically-pumped magnetometer (OPM) technology offers a number of compelling advantages over its SQUID predecessor for magnetoencephalography (MEG), many studies and viewpoints focus on issues of (i) scalp placement, with commensurate increases in sensitivity to weak magnetic fields and (ii) room temperature operation (without the need for baths of liquid helium to maintain superconducting properties of SQUIDs). This article addresses another unique and tantalizing opportunity-the ability for the OPM array to be "wearable", and thus to move with the participant. This is critical in adoption of naturalistic paradigms that move beyond "laboratory neuroscience" toward "real world neuroscience". It is also critically important in application to pediatric populations who cannot or will not remain still during conventional MEG scan procedures. Application to the developing infant brain will be considered as well as application to pediatric neuropsychiatric and developmental disorders, such as autism spectrum disorder. Rather than present solutions, this article will highlight the challenges faced by conventional SQUID-based cryo-MEG and explore the potential avenues for OPM-MEG to make a positive impact to the field of pediatric neuroscience.

Indexed as

auditoryautismoptically-pumped magnetometer (OPM)pediatricwearable

Identifiers

PMID39911606
PMCPMC11790644

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.