Evidence map›Paper›PMID 39911588›Full record

ArticleJournal of pharmaceutical policy and practice2025

Impact of pharmacist-led medication review among hemodialysis patients: a systematic review.

Ganesh Sritheran Paneerselvam, Chen Kah Yee, Muhammad Junaid Farrukh, Ana Yuda, Andi Hermansyah, Mohd Fadli Mohd Asmani, Ibrahim Abdullah, Long Chiau Ming

Abstract read
In one paragraph

Article in Journal of pharmaceutical policy and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ganesh Sritheran PaneerselvamSchool of Pharmacy, Taylor's University, Subang Jaya, Malaysia.ORCID https://orcid.org/0000-0002-9062-5092
Chen Kah YeeSchool of Pharmacy, Taylor's University, Subang Jaya, Malaysia.
Muhammad Junaid FarrukhFaculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia.
Ana YudaDepartment of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia.
Andi HermansyahDepartment of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia.
Mohd Fadli Mohd AsmaniSchool of Pharmacy, Management and Science University, Shah Alam, Malaysia.
Ibrahim AbdullahSchool of Pharmacy, Management and Science University, Shah Alam, Malaysia.
Long Chiau MingDepartment of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia.ORCID https://orcid.org/0000-0002-6971-1383

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Medication-related problems (DRPs) are common among hemodialysis (HD) patients, and pharmacist-led medication reviews have been shown to address such issues. However, the impact of these interventions and the specific types of DRPs among this patient group remain unclear. Objectives: This systematic review aimed to assess the impact of pharmacist-led medication reviews among HD patients, identify the most prevalent types of DRPs, and explore the factors associated with these problems. Methods: A systematic search was conducted across databases such as Results: After screening 343 articles, 10 studies (involving 1342 HD patients) were included. Nine studies were rated as high quality, and one as fair quality. The studies predominantly used prospective designs. A total of 4511 DRPs were identified, with suboptimal drug treatment, non-adherence to medications, and drug use without indication being the most common issues. Pharmacist interventions led to the resolution or reduction of DRPs, shorter hospital stays, improvement in laboratory outcomes, better quality of life (QoL), and enhanced patient understanding. However, interventions had minimal or no significant impact on reducing unplanned admissions, mortality rates, or improving medication adherence. The reduction in healthcare utilisation costs was inconsistent across studies. Conclusion: Pharmacist-led medication reviews were effective in resolving DRPs and improving clinical outcomes in HD patients, such as quality of life and lab values. However, their impact on healthcare utilisation and mortality remains inconclusive. Further research with longer follow-up is needed to assess the long-term economic outcomes of these interventions.

Indexed as

disease burdendrug safetyhemodialysisNon-communicable diseasepatient safetyrenal disease

Identifiers

PMID39911588
PMCPMC11795745

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.