ArticleRSC advances2025
Sticky tubes co-assembled by functionalised diphenylalanine and polydopamine nanoparticles form biocompatible antifouling coating.
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Predicting Supramolecular Self-Assembly of Peptide Structures with AlphaFold3.bioRxiv : the preprint server for biology · 2026Article
- Polydopamine-based Surface Modifications for Tissue Engineering and Biosensing: From Understanding Chemistry to Diverse Applications.JOM (Warrendale, Pa. : 1989) · 2025Article
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Authors and funding
6 authors.
Funding
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Abstract
The persistent challenge of biofouling, driven by the accumulation of microorganisms and biological residues on surfaces, undermines operational efficiency and safety across multiple industries. Functionalized peptide based biocompatible and supramolecular coating can provide a substantial solution to this crucial issue. This present study describes the formation of polydopamine-comprised sticky tubes through the co-assembly of an antifouling peptide P1 (FF-PFB) and Polydopamine Nanoparticles (PDA NPs) with an adhesive catechol moiety. To overcome the synthetic complications associated with the attachment of adhesive l-DOPA or dopamine with antifouling peptides, we have employed a simple co-assembly strategy. These co-assembled sticky tubes form a stable, biocompatible coating on desired surfaces (glass and aluminium) and resist fouling. The design consists of a diphenylalanine-based antifouling peptide covalently coupled with pentafluoro benzaldehyde (PFB), which could self-assemble into a stable functional coating through the adhesive catechol moiety of PDA NPs. This functional coating effectively resists bacterial and protein adhesion. These sticky tubes coated desired surfaces (glass and aluminium) exhibit excellent antifouling activity against both tested Gram (+)ve (
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Registered trials
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