Evidence map›Paper›PMID 39911483›Full record

ArticleFrontiers in veterinary science2024

The role of Ashwagandha in modulating gut parameters in dogs-a randomized double-blind placebo-controlled trial.

Kala Kumar Bharani, Ashok Kumar Devarasetti, Rajendar Bobbili, Amit Khurana, Donga Durga Veera Hanuman, Roupesh Gudepu, Swapna Guda

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kala Kumar BharaniDepartment of Pharmacology and Toxicology, School of Veterinary and Animal Sciences, Centurion University of Technology and Management, Paralakhemundi, India.
Ashok Kumar DevarasettiDepartment of Veterinary Biochemistry, College of Veterinary Science (CVSc), Warangal, India.
Rajendar BobbiliDepartment of Veterinary Pharmacology and Toxicology, College of Veterinary Science (CVSc), Hyderabad, India.
Amit KhuranaDepartment of Veterinary Pharmacology and Toxicology, College of Veterinary Science (CVSc), Hyderabad, India.
Donga Durga Veera HanumanDepartment of Veterinary Pharmacology and Toxicology, College of Veterinary Science (CVSc), Hyderabad, India.
Roupesh GudepuDepartment of Animal Nutrition, Nagpur Veterinary College, Maharashtra Animal and Fishery Sciences University, Nagpur, India.
Swapna GudaDepartment of Veterinary Pharmacology and Toxicology, College of Veterinary Science (CVSc), Hyderabad, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study explored the role of Methods: A randomized, double-blind, placebo-controlled trial was conducted in Telangana, India. Twelve healthy geriatric Beagle dogs aged 12-15 years were enrolled. The dogs were divided into two groups to receive ARE (15 mg/kg, once daily, orally, for 2 months) or a placebo control. Various parameters were assessed, including serum haematology, biochemical markers, stool parameters, and gut-microbiome parameters. Results: The erythrocyte counts and haemoglobin levels were significantly increased with ARE ( Conclusion: In summary, these findings suggest that ARE has gut health promoting benefits in healthy geriatric dogs by improving haematological and biochemical profiles; the levels of L-citrulline; propionic acid; and SCFA; thus, reducing age-related changes by modulating the microbiome and the associated metabolites.

Indexed as

adaptogenaging-related changesAshwagandha root extractgeriatric dogshealthy gutmicrobiome

Identifiers

PMID39911483
PMCPMC11794502

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.