Evidence map›Paper›PMID 39911479›Full record

ArticleFrontiers in veterinary science2024

Evaluating biomarkers in canine cytotoxic interface dermatitis reactions to account for clinical and histopathological similarities and differences.

Shriya Kannan, Neil B Wong, Grace E Ryan, Nia E R James, Ayodeji Ajayi, Janet E Lubov, Clement N David, Linda Wrijil, Nicholas A Robinson, Kelly Hughes and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in veterinary science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shriya KannanDepartment of Dermatology, UMass Chan Medical School, Worcester, MA, United States.
Neil B WongDepartment of Dermatology, UMass Chan Medical School, Worcester, MA, United States.
Grace E RyanDepartment of Dermatology, UMass Chan Medical School, Worcester, MA, United States.
Nia E R JamesDepartment of Dermatology, UMass Chan Medical School, Worcester, MA, United States.
Ayodeji AjayiDepartment of Dermatology, UMass Chan Medical School, Worcester, MA, United States.
Janet E LubovDepartment of Dermatology, UMass Chan Medical School, Worcester, MA, United States.
Clement N DavidNanoString Technologies, Seattle, WA, United States.
Linda WrijilPathology Department, Tufts Cummings School of Veterinary Medicine, North Grafton, MA, United States.
Nicholas A RobinsonPathology Department, Tufts Cummings School of Veterinary Medicine, North Grafton, MA, United States.
Kelly HughesPathology Department, Colorado State University, Fort Collins, CO, United States.
Ramon M AlmelaDepartment of Clinical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, MA, United States.
Jillian M RichmondDepartment of Dermatology, UMass Chan Medical School, Worcester, MA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytotoxic interface dermatitis (CID) is a pattern reaction predominantly at the dermo-epidermal junction that encapsulates numerous chronic non-communicable inflammatory skin conditions in which the basal keratinocytes are attacked by T-cell infiltrate leading to apoptosis, lymphocytic satellitosis and vacuolar degeneration. Though many diseases include CID, the type of clinical presentation and tissue patterns expressed from disease to disease varies. In this study, we evaluate the commonalities and discrepancies in significantly expressed biomarkers across several CID conditions to examine their impact on clinical presentations in canines. Among the uniquely expressed genes in each disease, we observed significantly expressed

Indexed as

canine (dog)cytotoxic interface dermatitis (CID)discoid lupus erythematosus (DLE)epitheliotropic lymphoma (EL)/cutaneous T cell lymphoma (CTCL)erythema multiformepemphiguspharmaco-transcriptomicsVogt–Koyanagi–Harada (VKH)

Identifiers

PMID39911479
PMCPMC11796617

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.