Evidence map›Paper›PMID 39911444›Full record

ArticleHeliyon2025

Differential quantity of key bioactive compounds and their antioxidative potential in novel apple genotypes: A correlative study for potential therapeutics.

Syed Mudassir Jeelani, Salwee Yasmin, Ashiq Hussain Lone, Javid Iqbal Mir, Mohammad Irfan, Vishal Dinkar, Wasim Hassan Raja, Sajad Un Nabi, Mahendra Kumar Verma, Geetika Malik and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Syed Mudassir JeelaniICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, India.
Salwee YasminICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, India.
Ashiq Hussain LoneICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, India.
Javid Iqbal MirICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, India.
Mohammad IrfanICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, India.
Vishal DinkarICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, India.
Wasim Hassan RajaICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, India.
Sajad Un NabiICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, India.
Mahendra Kumar VermaICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, India.
Geetika MalikICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, India.
Om Chand SharmaICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apples are among the most economically vital crops growing worldwide. The present study aimed to analyze the variation in the content of key bioactive principles and antioxidative potential of novel apple genotypes (developed through breeding techniques) along with their correlation for possible therapeutic insights. Using the HPLC method, the bioactive compounds of these apples were investigated, and their contribution to free radical scavenging activity by employing DPPH assay. HPLC analyses displayed concentration of bioactive compounds varies significantly among these genotypes with catechins, epicatechins, quercetin, and rutin were the key bioactive compounds. Principal Component Analysis results revealed a correlation between total phenolic content and antioxidative potential. It is also apparent that phenols are primary contributors to the antioxidant efficacy among the apple genotypes under investigation for potential therapeutic application. Besides, the study dispenses some valuable statistics for the production of novel apple genotypes having added phytochemicals for conventional and modern breeders.

Indexed as

Antioxidative potentialApple genotypesBioactive compoundsDPPHPCAPhenolics

Identifiers

PMID39911444
PMCPMC11795040

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.