ArticleHeliyon2025
Effective optical and treatment zone analysis by means of cross-over differences after lenticule extraction.
Article in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To determine the size of the effective optical and treatment zones after lenticule extraction procedures. Design: Retrospective case series. Methods: A fully automated method to determine the boundaries of the optical and treatment zones of a lenticule of tissue extracted from a cornea has been developed, in which the boundaries of the corrected area are derived from differences between post and preoperative maps of several corneal metrics by determining the smallest cross-over point along each semi-meridian. Results: The method has been applied to a pilot cohort of 84 eyes, clinical data showing average diameters of 6.56 ± 0.46 mm [5.25 to 7.51] and 8.49 ± 0.56 mm [6.58 to 9.52] for tangential anterior curvature and corneal thickness, respectively. Conclusions: The method provides a reliable and objective way to determine the size of a lenticule of tissue extracted from a cornea and it can be applied to any topo- or tomographic derived metric. Translational relevance: To determine the size of the effective optical and treatment zones after laser vision correction, a fully automated method was developed. The method is simple to implement and can be used to determine the actual size of a corneal correction and help titrating the planned size. The advantages of this algorithm over existing methods are its objectivity; automation; speed; resolution, accuracy and precision; the free-form boundary determination; and finally its support in determining centration and circularity.
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Registered trials
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