Evidence map›Paper›PMID 39911308›Full record

ArticleFrontiers in genetics2024

In silico design of an epitope-based vaccine ensemble for fasliolopsiasis.

Ruchishree Konhar, Kanhu Charan Das, Aiboklang Nongrum, Rohan Raj Samal, Shailesh Kumar Sarangi, Devendra Kumar Biswal

Abstract read
In one paragraph

Article in Frontiers in genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ruchishree KonharInformatics and Big Data, CSIR-Institute of Genomics and Integrative Biology, Delhi, India.
Kanhu Charan DasDepartment of Zoology, North-Eastern Hill University, Shillong, Meghalaya, India.
Aiboklang NongrumDepartment of Zoology, North-Eastern Hill University, Shillong, Meghalaya, India.
Rohan Raj SamalBioinformatics Centre, North-Eastern Hill University, Shillong, Meghalaya, India.
Shailesh Kumar SarangiBioinformatics Centre, North-Eastern Hill University, Shillong, Meghalaya, India.
Devendra Kumar BiswalDepartment of Zoology, North-Eastern Hill University, Shillong, Meghalaya, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Fasciolopsiasis, a food-borne intestinal disease is most common in Asia and the Indian subcontinent. Pigs are the reservoir host, and fasciolopsiasis is most widespread in locations where pigs are reared and aquatic plants are widely consumed. Human infection has been most commonly documented in China, Bangladesh, Southeast Asia, and parts of India. It predominates in school-age children, and significant worm burdens are not uncommon. The causal organism is Methods: Over the last decade, we have achieved major advances in our understanding of intestinal fluke biology by in-depth interrogation and analysis of evolving Results and discussion: This chimeric vaccine can now be tested experimentally and compared to other vaccine candidates to determine its potential influence on human health. Although the results are encouraging, additional validation is needed both

Indexed as

Fasciolopsis buskiimmune simulationintestinal flukeTLR2vaccine construct

Identifiers

PMID39911308
PMCPMC11794225

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.