Evidence map›Paper›PMID 39911303›Full record

ArticleOpen research Europe2024

IMMUnity Unveiled: A Translational NETwork for tackling PARKinson's Disease - IMMUPARKNET.

Mitilda Gugu, Shubhra Acharya, Dogukan Pira, Simona Poletti, Alessia di Flora, Tamara Saksida, Vladimirs Pilipenko, Marina Romero-Ramos, Franca Marino, Laura Muñoz Delgado and 5 more

Abstract read
In one paragraph

Article in Open research Europe, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Mitilda Gugu *Preclinical Department, Faculty of Technical Medical Sciences, University of Elbasan "Aleksandër Xhuvani", Elbasan, Albania.ORCID https://orcid.org/0000-0002-5064-3915
Shubhra Acharya *Luxembourg and Faculty of Science, Technology and Medicine, University of Luxembourg, Luxembourg, Luxembourg.ORCID https://orcid.org/0000-0003-2904-6566
Dogukan PiraFaculty of Medicine, Izmir University of Economics, Izmir, Turkey.
Simona PolettiDepartment of Translational Medicine, University of Eastern Piedmont, Novara, Italy.
Alessia di FloraCenter for Research in Medical Pharmacology, School of Medicine, University of Insubria, Varese, Lombardy, Italy.ORCID https://orcid.org/0000-0003-4199-4307
Tamara SaksidaInstitute for Biological Research "Siniša Stanković", National Institute of Republic of Serbia, University of Belgrade, Belgrade, Serbia.ORCID https://orcid.org/0000-0002-2527-3246
Vladimirs PilipenkoDepartment of Pharmacology, Faculty of Medicine, University of Latvia, Riga, Riga, Latvia.ORCID https://orcid.org/0000-0002-7098-7483
Marina Romero-RamosDanish Research Institute of Translational Neuroscience - DANDRITE & Department of Biomedicine, Aarhus University, Aarhus, Central Denmark Region, Denmark.
Franca MarinoCenter for Research in Medical Pharmacology, School of Medicine, University of Insubria, Varese, Lombardy, Italy.
Laura Muñoz DelgadoUnidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica, Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/CSIC, Universidad de Sevilla, Seville, Andalusia, Spain.
Neda NikolovskiInstitute for Biological Research "Siniša Stanković", National Institute of Republic of Serbia, University of Belgrade, Belgrade, Serbia.
Yasemin Gursoy OzdemirDepartment of Neurology, School of Medicine, Koç University, Istanbul, İstanbul, Turkey.
Dale LawsonUniversity of Eastern Piedmont, Novara, Italy.ORCID https://orcid.org/0009-0003-7837-1311
Cristoforo ComiDepartment of Translational Medicine, University of Eastern Piedmont, Novara, Italy.
Inês FigueiraNOVA Medica School | Faculdade de Ciências Médicas (NMS|FCM), Universidade Nova de Lisboa, Lisbon, Lisbon, Portugal.ORCID https://orcid.org/0000-0002-0860-8964

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) affects more than one million people in the EU. It currently has no definitive cure, meaning that patients rely only on symptomatic treatments, which themselves are burdened by side effects. The need for advancements in both knowledge and available treatments is thus strongly felt by patients, caregivers, and health operators. This unmet need sparked the idea of orchestrating a collaborative effort via a common network - IMMUPARKNET (The role of IMMUnity in tackling PARKinson's disease through a Translational NETwork). The IMMUPARKNET COST Action focuses on challenges in PD and its related crosstalk with immune response. Although widely recognized, the role of immunity in the onset and development of PD is still unclear. The main goal of IMMUPARKNET is to fill this knowledge gap by establishing an innovative, interdisciplinary research network and fostering exchanges of expertise among specialists from different countries and institutions. As we gather scientists and clinicians who study immunity in PD and related fields, IMMUPARKNET will establish the first nucleus of a multidisciplinary ecosystem that aims to harmonize efforts and approaches, both in research and clinical practice, to boost the development of ground-breaking treatments for PD. Through meetings, training schools, webinars, position papers, and review manuscripts, IMMUPARKNET will lead fruitful exchanges of know-how among experts in the field. The IMMUPARKNET structure revolves around 5 working groups, with a total of 157 active members from 34 different countries. Of these active members, 58.5% are young researchers, while 67.5% come from Inclusiveness Target Countries (ITC - less research-intensive COST Members; https://www.cost.eu/about/members/). IMMUPARKNET output will facilitate the improved sharing and development of research resources, straightening the road to novel treatments and identifying where existing ones can be repurposed, all, ultimately and hopefully, finding a cure for PD.

Indexed as

immune responsenetworkParkinson's disease

Identifiers

PMID39911303
PMCPMC11795026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.