ArticleOsteoarthritis and cartilage open2025
Friction of osteoarthritic cartilage with patient-specific synovial fluid: Effect of different loading conditions.
Article in Osteoarthritis and cartilage open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Meniscal centralization restores meniscus-cartilage contact mechanics after posterior root repair: a biomechanical in-silico study.Journal of orthopaedic surgery and research · 2026Article
- The influence of infrapatellar fat pad resection on knee joint friction and damping: An in vitro study in New Zealand white rabbits.Journal of the mechanical behavior of biomedical materials · 2026Article
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Authors and funding
5 authors.
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Abstract
Objective: The objective of this study was to quantify the friction coefficients of degenerated human cartilage lubricated with patient-specific synovial fluid under four different loading regimes in order to identify those regimes that cause the highest friction. Method: Lateral tibial plateaus and synovial fluid samples were obtained from six patients undergoing total knee replacement surgery. Friction tests were performed on cylindrical samples using an established cartilage against glass tribometer. Four different loading regimes were applied, representing physiologic loads and velocities observed during daily activities. To account for effects of osteoarthritis (OA)-related alterations in the synovial fluid (SF) on friction, patient-specific SF was used as lubricant. Friction coefficients were derived from the first (μ Results: Under stance phase conditions, friction was lowest at the beginning of testing (μ Conclusion: The friction properties of degenerated cartilage samples indicated a strong dependency on the loading regime, whereby prolonged stance phase loading led to the highest time-dependent increase in friction. Moreover, our data suggested that osteoarthritic synovial fluid was sufficient to provide low cartilage friction.
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