ArticleStats2025
Bidirectional f-Divergence-Based Deep Generative Method for Imputing Missing Values in Time-Series Data.
Article in Stats, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Pseudotime-conditioned diffusion models for imputing time-series single-cell data.Bioinformatics advances · 2026Article
- Blue Noise-based Generative Models for the Imputation of Time-series Data.International Conference on Information Science and Technology. International Conference on Information Science and Technology · 2025Article
- Gene Regulatory Network Inference from Pseudotime-Ordered scRNA-seq Data via Time-Lagged Divergence Measures.Bioinformatics research and applications : ... international symposium, ISBRA ... proceedings. ISBRA (Conference) · 2025Article
- Reconstructing Dynamic Gene Regulatory Networks Using f-Divergence from Time-Series scRNA-Seq Data.Current issues in molecular biology · 2025Article
- Time-Varying Gene Regulatory Networks Inference Using KL Divergence from Single Cell Data.Proceedings of the ... International Conference on Bioinformatics and Biomedical Technology · 2025Article
- Anomaly Detection in High-Dimensional Time Series Data with Scaled Bregman Divergence.Algorithms · 2025Article
- tBN-CSDI: a time-varying blue noise-based diffusion model for time-series imputation.Bioinformatics advances · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Imputing missing values in high-dimensional time-series data remains a significant challenge in statistics and machine learning. Although various methods have been proposed in recent years, many struggle with limitations and reduced accuracy, particularly when the missing rate is high. In this work, we present a novel f-divergence-based bidirectional generative adversarial imputation network, tf-BiGAIN, designed to address these challenges in time-series data imputation. Unlike traditional imputation methods, tf-BiGAIN employs a generative model to synthesize missing values without relying on distributional assumptions. The imputation process is achieved by training two neural networks, implemented using bidirectional modified gated recurrent units, with f-divergence serving as the objective function to guide optimization. Compared to existing deep learning-based methods, tf-BiGAIN introduces two key innovations. First, the use of f-divergence provides a flexible and adaptable framework for optimizing the model across diverse imputation tasks, enhancing its versatility. Second, the use of bidirectional gated recurrent units allows the model to leverage both forward and backward temporal information. This bidirectional approach enables the model to effectively capture dependencies from both past and future observations, enhancing its imputation accuracy and robustness. We applied tf-BiGAIN to analyze two real-world time-series datasets, demonstrating its superior performance in imputing missing values and outperforming existing methods in terms of accuracy and robustness.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.