Evidence map›Paper›PMID 39911013›Full record

ArticleAddiction (Abingdon, England)2025

Validation of the alcohol, smoking and substance involvement screening test (ASSIST) for identifying methamphetamine use among people on methadone maintenance treatment in Vietnam.

Truc Thanh Thai, Diep Bich Nguyen, Trang Thu Nguyen, Hai-Van Thi Hoang, Michael Li, Li Li, Tuong-Vi Thi Vu, Lan-Phuong Thi Tran, Dung Van Do, Steve Shoptaw and 1 more

Abstract readValidation Study
In one paragraph

Article in Addiction (Abingdon, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Interpol review of forensic drug chemistry, 2022-2025.Forensic science international. Synergy · 2026
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Truc Thanh ThaiFaculty of Public Health, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.ORCID https://orcid.org/0000-0003-2512-8281
Diep Bich NguyenCenter for Training and Research on Substance Use & HIV, Hanoi Medical University, Ha Noi City, Vietnam.
Trang Thu NguyenCenter for Training and Research on Substance Use & HIV, Hanoi Medical University, Ha Noi City, Vietnam.
Hai-Van Thi HoangDepartment of Global Health, Institute of Preventive Medicine and Public Health, Hanoi Medical University, Ha Noi City, Vietnam.
Michael LiCenter for Behavioral and Addiction Medicine, Department of Family Medicine, University of California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0003-2457-604X
Li LiDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0002-3402-142X
Tuong-Vi Thi VuVietnam HIV Addiction Technology Transfer Center, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Lan-Phuong Thi TranVietnam HIV Addiction Technology Transfer Center, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Dung Van DoFaculty of Public Health, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Steve ShoptawCenter for Behavioral and Addiction Medicine, Department of Family Medicine, University of California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0002-3583-0026
Giang Minh LeCenter for Training and Research on Substance Use & HIV, Hanoi Medical University, Ha Noi City, Vietnam.

Funding

UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Sung-Jae Lee · 1997 to 2026
$53.5M
Screen, Treat and Retain People with Primary Meth Use Disorder at MMT Clinics (STAR-OM+)R01DA050486 · NIDA · HANOI MEDICAL UNIVERSITY · PI LE, GIANG M, SHOPTAW, STEVEN J · 2020 to 2024
$2.3M
Trajectories of socially regulated gene expression, methamphetamine use, and viral load among HIV-positive men who have sex with men (MSM) receiving contingency managementK01DA051329 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LI, MICHAEL JONATHAN · 2021 to 2025
$947k
NIDA NIH HHS 1R01DA050486-01NIDA NIH HHS K01 DA051329NIDA NIH HHS R01 DA050486NIMH NIH HHS P30 MH058107
6 · The paper itself

Abstract

BACKGROUND AND

aimsIdentifying those who use methamphetamine or are at high risk of using methamphetamine is essential so that early, appropriate intervention can be made. This study evaluated the use of the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) for identifying methamphetamine use among people on methadone maintenance treatment (MMT) in Vietnam.

methodsFrom June 2021 to May 2023, all people on MMT at 15 methadone clinics in Hanoi and Ho Chi Minh City, Vietnam, were invited to participate in this study. Participants underwent a face-to-face interview to complete the 8-item ASSIST. Participants also had a urine drug test (UDT) for methamphetamine use. Discriminant properties of the ASSIST were evaluated using UDT as the reference.

resultsAmong 6709 participants, 10.7% (n = 717) tested positive for methamphetamine use via UDT. The ASSIST demonstrated robust discriminant abilities to identify those who used methamphetamine [area under the curve (AUC) = 0.872; 95% confidence interval (CI) = 0.856-0.887]. At the commonly used cutoff of 4, the ASSIST had a sensitivity of 83.8% and a specificity of 82.0%. At this cutoff, 82.2% of the ASSIST results aligned with UDT outcomes (kappa coefficient = 0.41, P < 0.001) and the ASSIST identified a prevalence of 25.0%. At higher cutoffs, the sensitivity of the ASSIST decreased but both the specificity and the agreement with the UDT results increased.

conclusionsThe Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) appears to be reliable and valid in identifying methamphetamine use among people on methadone treatment in Vietnam. Cutoff adjustments may help to reduce false positive rates.

Indexed as

Amphetamine-Related DisordersMethadoneMethamphetamineOpiate Substitution TreatmentSubstance Abuse DetectionAdultFemaleHumansMaleMiddle AgedSensitivity and SpecificitySmokingVietnamYoung AdultMethadoneMethamphetamineASSISTmethadonemethamphetamineurine drug testvalidationVietnam

Identifiers

PMID39911013
PMCPMC12129688

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.