Evidence map›Paper›PMID 39910977›Full record

ArticleActa biochimica et biophysica Sinica2025

mTOR-related linc-PMB promotes mitochondrial biogenesis via stabilizing SIRT1 mRNA through binding to the HuR protein.

Qian Chen, Huaying Zhang, Daokun Wang, Wenjing Liao, Yazhou Liu, Yurui Cai, Siyou Wang, Mengqian Yu

Abstract read
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In one paragraph

Article in Acta biochimica et biophysica Sinica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qian ChenDepartment of Laboratory Medicine, Chengdu Second People's Hospital, Chengdu 610017, China.
Huaying ZhangDepartment of Clinical Laboratory, Hangzhou Traditional Chinese Medicine Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou 310000, China.
Daokun WangDepartment of Laboratory Medicine, Chengdu Second People's Hospital, Chengdu 610017, China.
Wenjing LiaoDepartment of Laboratory Medicine, Chengdu Second People's Hospital, Chengdu 610017, China.
Yazhou LiuDepartment of Laboratory Medicine, Chengdu Second People's Hospital, Chengdu 610017, China.
Yurui CaiDepartment of Laboratory Medicine, Chengdu Second People's Hospital, Chengdu 610017, China.
Siyou WangDepartment of Laboratory Medicine, Chengdu Second People's Hospital, Chengdu 610017, China.
Mengqian YuZhejiang Provincial Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women's Hospital and Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou 310000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondrial dysfunction is implicated in numerous disorders, including type 2 diabetes, Alzheimer's disease and cancer. Long non-coding RNAs (lncRNAs) are emerging as pivotal regulators of cellular energy metabolism, yet their roles remain largely unclear. In this study, we identify an lncRNA named linc-PMB, which is associated with mTOR and promotes mitochondrial biogenesis, through microarray analysis. We demonstrate that the knockdown of

Indexed as

ELAV-Like Protein 1MitochondriaOrganelle BiogenesisRNA, Long NoncodingRNA, MessengerSirtuin 1TOR Serine-Threonine KinasesHumansPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaRNA StabilityELAVL1 protein, humanELAV-Like Protein 1MTOR protein, humanPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPPARGC1A protein, humanRNA, Long NoncodingRNA, MessengerSIRT1 protein, humanSirtuin 1TOR Serine-Threonine KinasesHuRlong non-coding RNAmitochondrial biogenesismTORSIRT1

Identifiers

PMID39910977
PMCPMC12367985

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.