Evidence map›Paper›PMID 39910767›Full record

ArticleRisk analysis : an official publication of the Society for Risk Analysis2025

Risk analysis approaches for microbial ingredients in microbial-based cleaning products.

Diane Boesenberg, Chris Brueck, Cindy Chhuon, James Kim, Arthur J Miller, Gerard J Stijntjes, Heidi Vedel, Richard C Whiting, J Ian Van Trump

Abstract read
In one paragraph

Article in Risk analysis : an official publication of the Society for Risk Analysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Risk analysis approaches for microbial ingredients in microbial-based cleaning products.Risk analysis : an official publication of the Society for Risk Analysis · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Diane BoesenbergExponent, Inc., Washington, District of Columbia, USA.
Chris BrueckExponent, Inc., Washington, District of Columbia, USA.
Cindy ChhuonAISE, Brussels, Belgium.
James KimAmerican Cleaning Institute (ACI), Washington, District of Columbia, USA.
Arthur J MillerExponent, Inc., Washington, District of Columbia, USA.
Gerard J StijntjesProcter and Gamble, Strombeek-Bever, Belgium.
Heidi VedelIFF, Kongens Lyngby, Denmark.
Richard C WhitingExponent, Inc., Washington, District of Columbia, USA.
J Ian Van TrumpExponent, Inc., Washington, District of Columbia, USA.

Funding

The American Cleaning Institute funded the work on this paper as directed by Dr. James Kim
6 · The paper itself

Abstract

Microbial-based cleaning products (MBCPs) are an emerging class of cleaning products that contain viable microorganisms, often bacteria or bacterial endospores, as intentionally added formulation ingredients for cleaning and/or odor control. Although several well-established methodologies exist to support risk analysis for conventional chemical-based cleaning products, at present there are no widely recognized methods or commonly utilized frameworks to support risk analysis for use of microbial ingredients present in MBCPs, specifically. The purpose of this work is to provide information to MBCP manufacturers and regulators that can be used to assist in developing their own approaches to MBCP risk assessment. As part of this assessment, potential hazards associated with use of bacterial or bacterial endospore ingredients of MBCPs can be adequately characterized, assessed, and managed as part of both product development and ongoing product stewardship. Accordingly, this document summarizes potential approaches to support strain-level identification of microbial ingredient(s), evaluate their hazards and potential for human exposure, and assess their potential effects following such exposures to different human populations. Recommendations for both hazard and risk characterization are discussed. Additionally, guidance is provided to support decision-making by risk managers, including guidance for the development of risk communication strategies, where appropriate, to mitigate the identified risks. Properly applied, the conceptual approaches described herein may facilitate the standardization and more consistent application of appropriate risk analysis procedures tailored to suit microbial ingredients present in MBCPs. Beyond their utility in assessing microbial ingredients commonly used in MBCPs today, these same approaches may help companies and regulators consider and manage risks for new microbial ingredients that may be utilized in future MBCP formulations.

Indexed as

BacteriaDetergentsHousehold ProductsHumansRisk AssessmentDetergentsmicrobial cleaning productsmicrobiological hazardsproduct safetyrisk analysis

Identifiers

PMID39910767
PMCPMC12396937

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.