Evidence map›Paper›PMID 39910494›Full record

SynthesisBMC public health2025

Effect of maternal HIV infection on birth outcomes among HIV positive women in Sub Saharan Africa: a systematic review and meta-analysis.

Worku Necho Asferie, Tigabu Munye Aytenew, Amare Kassaw, Habtamu Shimels Hailemeskel, Solomon Demis Kebede, Bosena Tebeje Gashaw, Demewoz Kefale

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Worku Necho AsferieDepartment of Maternal and Neonatal Health Nursing, College of Health Sciences, Debre Tabor University, P.O.Box:272, Debre Tabor, Ethiopia. workunecho@gmail.com.
Tigabu Munye AytenewDepartment of Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Amare KassawDepartment of Pediatrics and Child Health Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Habtamu Shimels HailemeskelDepartment of Maternal and Neonatal Health Nursing, College of Health Sciences, Debre Tabor University, P.O.Box:272, Debre Tabor, Ethiopia.
Solomon Demis KebedeDepartment of Maternal and Neonatal Health Nursing, College of Health Sciences, Debre Tabor University, P.O.Box:272, Debre Tabor, Ethiopia.
Bosena Tebeje GashawSchool of Midwifery, College of Health Science, Jimma University, Jimma Town, Ethiopia.
Demewoz KefaleDepartment of Pediatrics and Child Health Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHIV is remaining the public health issues with an estimated of 39 million peoples are living with the virus till 2022. HIV positive pregnant women are at a greater risk of adverse birth outcomes including low birth weight (LBW), preterm delivery and perinatal mortality. Thus, this systematic review aimed to examine the pooled effect of maternal HIV infection on birth outcomes in Sub Saharan Africa.

methodA systematic literature searches were done from PubMed, Hinari, Google scholar and online research repositories. All observational studies (January/2012 to January 01/2024) reporting the effects of maternal HIV on birth outcomes among HIV positive women in Sub Saharan Africa were included. Heterogeneity between studies was assessed using I

resultA total of 19 articles met inclusion criteria and included in this systematic review. About 104,840 mothers were involved in this analysis. Maternal HIV infection had significant effects for giving low birth weight babies 9.68, 95%CI (6.72, 12.64), and preterm delivery 1.72; 95% CI: (1.49, 1.95) among HIV positive women in Sub Saharan Africa. Furthermore, the pooled estimate exhibited that maternal HIV had no risk for perinatal mortality among women living with HIV as compared to HIV negative women.

conclusionWomen living with HIV are at greater risk for giving low birth weight babies, preterm delivery than HIV negative women. We recommend that Health care providers and other stakeholders should focus on maternal HIV screening and providing special care to protect them from adverse birth outcomes during antenatal period.

Indexed as

HIV InfectionsPregnancy Complications, InfectiousPregnancy OutcomeAfrica South of the SaharaFemaleHumansInfant, Low Birth WeightInfant, NewbornPregnancyPremature BirthBirth outcomeHIV positive womenMaternal HIVSub Saharan Africa

Identifiers

PMID39910494
PMCPMC11796279

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.