Evidence map›Paper›PMID 39910310›Full record

ArticleNature2025

H-bonded organic frameworks as ultrasound-programmable delivery platform.

Wenliang Wang, Yanshu Shi, Wenrui Chai, Kai Wing Kevin Tang, Ilya Pyatnitskiy, Yi Xie, Xiangping Liu, Weilong He, Jinmo Jeong, Ju-Chun Hsieh and 12 more

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Wenliang Wang *Biomedical Engineering, Cockrell School of Engineering, The University of Texas at Austin, Austin, TX, USA.ORCID 0000-0003-0575-8139
Yanshu Shi *Department of Chemistry, The University of Texas at San Antonio, San Antonio, TX, USA.
Wenrui Chai *Freshman Research Initiative, College of Natural Sciences, The University of Texas at Austin, Austin, TX, USA.
Kai Wing Kevin Tang *Biomedical Engineering, Cockrell School of Engineering, The University of Texas at Austin, Austin, TX, USA.
Ilya PyatnitskiyBiomedical Engineering, Cockrell School of Engineering, The University of Texas at Austin, Austin, TX, USA.
Yi XieDepartment of Chemistry, The University of Texas at San Antonio, San Antonio, TX, USA.
Xiangping LiuBiomedical Engineering, Cockrell School of Engineering, The University of Texas at Austin, Austin, TX, USA.ORCID 0000-0001-6554-8411
Weilong HeBiomedical Engineering, Cockrell School of Engineering, The University of Texas at Austin, Austin, TX, USA.
Jinmo JeongBiomedical Engineering, Cockrell School of Engineering, The University of Texas at Austin, Austin, TX, USA.ORCID 0000-0002-6088-2856
Ju-Chun HsiehBiomedical Engineering, Cockrell School of Engineering, The University of Texas at Austin, Austin, TX, USA.
Anakaren Romero LozanoBiomedical Engineering, Cockrell School of Engineering, The University of Texas at Austin, Austin, TX, USA.ORCID 0000-0001-5481-8527
Brinkley ArtmanBiomedical Engineering, Cockrell School of Engineering, The University of Texas at Austin, Austin, TX, USA.
Xi ShiDepartment of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
Nicole HoeferCenter for Electron Microscopy and Analysis, The Ohio State University, Columbus, OH, USA.
Binita ShresthaBiomedical Engineering, Cockrell School of Engineering, The University of Texas at Austin, Austin, TX, USA.
Noah B SternBiomedical Engineering, Cockrell School of Engineering, The University of Texas at Austin, Austin, TX, USA.ORCID 0000-0002-6390-8476
Wei ZhouCenter for Neutron Research, National Institute of Standards and Technology, Gaithersburg, MD, USA.ORCID 0000-0002-5461-3617
David W McCombCenter for Electron Microscopy and Analysis, The Ohio State University, Columbus, OH, USA.ORCID 0000-0003-3763-9652
Tyrone PorterBiomedical Engineering, Cockrell School of Engineering, The University of Texas at Austin, Austin, TX, USA.
Graeme HenkelmanFreshman Research Initiative, College of Natural Sciences, The University of Texas at Austin, Austin, TX, USA.ORCID 0000-0002-0336-7153
Banglin ChenDepartment of Chemistry, The University of Texas at San Antonio, San Antonio, TX, USA. banglin.chen@utsa.edu.ORCID 0000-0001-8707-8115
Huiliang WangBiomedical Engineering, Cockrell School of Engineering, The University of Texas at Austin, Austin, TX, USA. evanwang@utexas.edu.ORCID 0000-0003-4063-270X

Funding

Comprehensive Training Program in Imaging Science and InformaticsT32EB007507 · NIBIB · UNIVERSITY OF TEXAS AT AUSTIN · PI MARKEY, MIA K, RYLANDER, HENRY GRADY · 2009 to 2024
$2.7M
Non-Invasive and Non-Viral Sono-OptogeneticsR35GM147408 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI Huiliang Wang · 2022 to 2026
$2.0M
NIBIB NIH HHS T32 EB007507NIGMS NIH HHS R35 GM147408
6 · The paper itself

Abstract

The precise control of mechanochemical activation within deep tissues using non-invasive ultrasound holds profound implications for advancing our understanding of fundamental biomedical sciences and revolutionizing disease treatments

Indexed as

Drug Delivery SystemsUltrasonic WavesAnimalsClozapineDesigner DrugsHydrogen BondingMaleMiceNanoparticlesPorosityRatsClozapineclozapine N-oxideDesigner Drugs

Identifiers

PMID39910310
PMCPMC12038167

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.