Evidence map›Paper›PMID 39910114›Full record

ArticleScientific reports2025

A deep ensemble learning framework for glioma segmentation and grading prediction.

Liang Wen, Hui Sun, Guobiao Liang, Yue Yu

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Liang WenGeneral Hospital of Northern Theater Command, Shenyang, 110122, China. wenliang0813@sina.com.
Hui SunCollege of Information Science and Engineering, Northeastern University, Shenyang, 110819, China.
Guobiao LiangGeneral Hospital of Northern Theater Command, Shenyang, 110122, China.
Yue YuCollege of Information Science and Engineering, Northeastern University, Shenyang, 110819, China.

Funding

Fundamental Research Funds for the Central Universities N2404015Fundamental Research Funds for the Central Universities of China N2404013Liaoning Revitalization Talents Program XLYC2008020National Key Research and Development Program of China 2022YFB2703304National Natural Science Foundation of China 52074064Natural Science Foundation of Science and Technology Department of Liaoning Province 2021-BS-054
6 · The paper itself

Abstract

The segmentation and risk grade prediction of gliomas based on preoperative multimodal magnetic resonance imaging (MRI) are crucial tasks in computer-aided diagnosis. Due to the significant heterogeneity between and within tumors, existing methods mainly rely on single-task approaches, overlooking the inherent correlation between segmentation and grading tasks. Furthermore, the limited availability of glioma grading data presents further challenges. To address these issues, we propose a deep-ensemble learning framework based on multimodal MRI and the U-Net model, which simultaneously performs glioma segmentation and risk grade prediction. We introduce asymmetric convolution and dual-domain attention in the encoder, fully integrating effective information from different modalities, enhancing the extraction of features from critical regions, and constructing a dual-branch decoder that combines spatial features and global semantic information for both segmentation and grading. In addition, we propose a weighted composite adaptive loss function to balance the optimization objectives of the two tasks. Our experimental results on the BraTS dataset demonstrate that our method outperforms state-of-the-art methods, yielding superior segmentation accuracy and precise risk grade prediction.

Indexed as

Brain NeoplasmsDeep LearningEnsemble LearningGliomaDiagnosis, Computer-AssistedHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingNeoplasm GradingAttention mechanismDeep-ensemble frameworkDeep learningGliomaSegmentation and grading prediction

Identifiers

PMID39910114
PMCPMC11799385

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.