Evidence map›Paper›PMID 39910082›Full record

ArticleScientific reports2025

Integrating electrocardiogram and fundus images for early detection of cardiovascular diseases.

K A Muthukumar, Dhruva Nandi, Priya Ranjan, Krithika Ramachandran, Shiny Pj, Anirban Ghosh, Ashwini M, Aiswaryah Radhakrishnan, V E Dhandapani, Rajiv Janardhanan

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

K A MuthukumarUniversity of Petroleum and Energy Studies, Dehradun, Uttarakhand, India. muthukumar9890@gmail.com.
Dhruva Nandi *Faculty of Medicine and Health Sciences , SRM Medical College Hospital and Research Centre, SRM IST, Kattankulathur, Chengalpattu, Tamil Nadu, India.
Priya Ranjan *University of Petroleum and Energy Studies, Dehradun, Uttarakhand, India.
Krithika Ramachandran *Centre for High Impact Neuroscience and Translational Applications, TCG Crest, Kolkata, West Bengal, India.
Shiny Pj *Faculty of Medicine and Health Sciences , SRM Medical College Hospital and Research Centre, SRM IST, Kattankulathur, Chengalpattu, Tamil Nadu, India.
Anirban Ghosh *Department of Electronics and Communication, SRM University AP, Neerukonda, Andhra Pradesh, India.
Ashwini M *Ashwini Eye Care, Chennai, Tamil Nadu, India.
Aiswaryah Radhakrishnan *Faculty of Medicine and Health Sciences , SRM Medical College Hospital and Research Centre, SRM IST, Kattankulathur, Chengalpattu, Tamil Nadu, India.
V E Dhandapani *Sri Kalpana Heart Care, Chennai, Tamil Nadu, India.
Rajiv Janardhanan *Faculty of Medicine and Health Sciences , SRM Medical College Hospital and Research Centre, SRM IST, Kattankulathur, Chengalpattu, Tamil Nadu, India. rajivj@srmist.edu.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases (CVD) are a predominant health concern globally, emphasizing the need for advanced diagnostic techniques. In our research, we present an avant-garde methodology that synergistically integrates ECG readings and retinal fundus images to facilitate the early disease tagging as well as triaging of the CVDs in the order of disease priority. Recognizing the intricate vascular network of the retina as a reflection of the cardiovascular system, alongwith the dynamic cardiac insights from ECG, we sought to provide a holistic diagnostic perspective. Initially, a Fast Fourier Transform (FFT) was applied to both the ECG and fundus images, transforming the data into the frequency domain. Subsequently, the Earth Mover's Distance (EMD) was computed for the frequency-domain features of both modalities. These EMD values were then concatenated, forming a comprehensive feature set that was fed into a Neural Network classifier. This approach, leveraging the FFT's spectral insights and EMD's capability to capture nuanced data differences, offers a robust representation for CVD classification. Preliminary tests yielded a commendable accuracy of 84%, underscoring the potential of this combined diagnostic strategy. As we continue our research, we anticipate refining and validating the model further to enhance its clinical applicability in resource limited healthcare ecosystems prevalent across the Indian sub-continent and also the world at large.

Indexed as

Cardiovascular DiseasesElectrocardiographyFundus OculiEarly DiagnosisFourier AnalysisHumansNeural Networks, ComputerCNNCVD predictionEMDFundus image

Identifiers

PMID39910082
PMCPMC11799439

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.