Evidence map›Paper›PMID 39910005›Full record

ReviewReviews in endocrine & metabolic disorders2025

From pituitary cells to prostate gland in health and disease: direct and indirect endocrine connections.

André Sarmento-Cabral, Antonio C Fuentes-Fayos, Fernando Mata Ordoñez, Antonio J León-González, Antonio J Martínez-Fuentes, Manuel D Gahete, Raúl M Luque

Abstract readReview
In one paragraph

Review in Reviews in endocrine & metabolic disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

André Sarmento-CabralMaimonides Biomedical Research Institute of Cordoba (IMIBIC), Avda. Menéndez Pidal s/n., Cordoba, 14004, Spain. andre.cabral@imibic.org.ORCID 0000-0002-1204-0371
Antonio C Fuentes-FayosMaimonides Biomedical Research Institute of Cordoba (IMIBIC), Avda. Menéndez Pidal s/n., Cordoba, 14004, Spain.ORCID 0000-0003-2069-4823
Fernando Mata OrdoñezMaimonides Biomedical Research Institute of Cordoba (IMIBIC), Avda. Menéndez Pidal s/n., Cordoba, 14004, Spain.ORCID 0000-0003-4126-577X
Antonio J León-GonzálezMaimonides Biomedical Research Institute of Cordoba (IMIBIC), Avda. Menéndez Pidal s/n., Cordoba, 14004, Spain.ORCID 0000-0003-2668-8205
Antonio J Martínez-FuentesMaimonides Biomedical Research Institute of Cordoba (IMIBIC), Avda. Menéndez Pidal s/n., Cordoba, 14004, Spain.ORCID 0000-0003-0994-1037
Manuel D GaheteMaimonides Biomedical Research Institute of Cordoba (IMIBIC), Avda. Menéndez Pidal s/n., Cordoba, 14004, Spain.ORCID 0000-0002-4578-2179
Raúl M LuqueMaimonides Biomedical Research Institute of Cordoba (IMIBIC), Avda. Menéndez Pidal s/n., Cordoba, 14004, Spain. raul.luque@uco.es.ORCID 0000-0002-7585-1913

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prostate gland is an endocrine-sensitive organ responding to multiple stimuli. Its development and function are regulated by multiple hormones (i.e. steroids such as androgens, estrogens and glucocorticoids) but also by other key hormonal systems such as those comprised by insulin-like growth factor 1 and insulin, which are sourced by different tissues [e.g. testicles/adrenal-gland/adipose-tissue/liver/pancreas, etc.). Particularly important for the endocrine control of prostatic pathophysiology and anatomy are hormones produced and/or secreted by different cell types of the pituitary gland [growth-hormone, luteinizing-hormone, follicle-stimulating hormone, and prolactin, oxytocin, arginine-vasopressin and melanocyte-stimulating hormone], which affect prostate gland function either directly or indirectly under physiological and pathophysiological conditions [e.g. metabolic dysregulation (e.g. obesity), and prostate transformations (e.g. prostate cancer)]. This review summarizes the impact of all pituitary hormone types on prostate gland under these diverse conditions including in vivo and in vitro studies.

Indexed as

Pituitary GlandPituitary HormonesProstateProstatic DiseasesAnimalsHumansMaleProstatic NeoplasmsPituitary HormonesEndocrine regulationHormonesObesityPituitaryProstateProstate cancer

Identifiers

PMID39910005
PMCPMC11920336

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.