ArticleNaunyn-Schmiedeberg's archives of pharmacology2025
Sustainable streptomycin-based Ag nanoparticle synthesis and study of the cytotoxicity.
Article in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Antibiotic resistance is one of the major problems of our time, which can be addressed by the use of different nanoparticles synthesized using antibiotics. The interaction between nanoparticles and biological systems is dynamic, which makes them extremely powerful for applications in the biomedical field. In this work, silver nanoparticles (Ag NPs) were synthesized with streptomycin and characterized by TEM, XRD, and UV-VIS. The synthesis resulted in the formation of spherical particles in the size range of 10-20 nm, which did not show any signs of aggregation after several days, facilitating their ease of use. Cytotoxicity studies of the synthesized AgNPs were performed by flow cytometry on A549 lung cancer cells after 24 h of exposure. At a concentration of 0.02 mM AgNP, the live cell ratio did not differ significantly from the control, but LC
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