Evidence map›Paper›PMID 39909862›Full record

ArticleInterdisciplinary cardiovascular and thoracic surgery2025

Pulmonary expanded polytetrafluoroethylene conduits with a hand-sewn tricuspid valve.

Shunsuke Matsushima, Ryota Takahashi, Sara Kubo, Akihiko Higashida, Yoshihiro Oshima, Hironori Matsuhisa

Abstract read
In one paragraph

Article in Interdisciplinary cardiovascular and thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Shunsuke MatsushimaDepartment of Cardiovascular Surgery, Kobe Children's Hospital, Kobe, Japan.ORCID 0000-0002-9415-5788
Ryota TakahashiDepartment of Cardiovascular Surgery, Kobe Children's Hospital, Kobe, Japan.
Sara KuboDepartment of Cardiovascular Surgery, Kobe Children's Hospital, Kobe, Japan.
Akihiko HigashidaDepartment of Cardiovascular Surgery, Kobe Children's Hospital, Kobe, Japan.
Yoshihiro OshimaDepartment of Cardiovascular Surgery, Kobe Children's Hospital, Kobe, Japan.
Hironori MatsuhisaDepartment of Cardiovascular Surgery, Kobe Children's Hospital, Kobe, Japan.ORCID 0000-0003-3242-3545

Funding

JSPS KAKENHI 24K19416Nakatani Foundation 2022S115
6 · The paper itself

Abstract

objectivesThe biocompatibility of expanded polytetrafluoroethylene in the pulmonary position seems better than allogenic or xenogeneic reactivity. This study reviewed the application of pulmonary expanded polytetrafluoroethylene conduits having a hand-sewn tricuspid valve with diameters of 18-24 mm.

methodsAll patients receiving this conduit between 2010 and 2022 were evaluated. A 0.1-mm-thick membrane and a standard-wall tube of expanded polytetrafluoroethylene were used for cusp and conduit material, respectively.

resultsEighty-four consecutive patients were included. The median operative age and weight were 12 (range, 1.2-40) years and 34 (range, 9.1-82) kg, respectively. Eighteen-, 20-, 22- and 24-mm conduits were used in 19, 5, 3 and 57 patients, respectively. The overall survival was 94% at 5 and 10 years with four non-valve-related deaths. There were five conduit replacements, all for 18-mm conduit stenosis. Freedom from conduit replacement was 98% and 83% at 5 and 10 years, respectively. Freedom from conduit stenosis ≥ moderate was 83% and 54% at 5 and 10 years, respectively. Freedom from pulmonary regurgitation ≥ moderate was 98% at 5 and 10 years. Linear mixed-effects models with echocardiographic data implied that 24-mm conduits functioned with a peak velocity <3.0 m/s and without moderate/severe regurgitation in patients with a body weight of up to 75 kg and a body surface area of up to 2.0 m2 for >12 years postoperatively.

conclusionsThis conduit has shown favourable clinical outcomes and is a valid alternative, especially in young patients with increased risk for early failure of the existing products.

Indexed as

congenital heart diseaseexpanded polytetrafluoroethylene conduithand-sewn valvepediatric patientpulmonary valve replacementright ventricular outflow tract reconstruction

Identifiers

PMID39909862
PMCPMC11997764

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.