Evidence map›Paper›PMID 39909832›Full record

Trial reportThe clinical respiratory journal2025

Effect of Precise Pulmonary Rehabilitation Nursing Intervention Combined With Simultaneous Inhalation Therapy and Noninvasive Ventilation for Chronic Obstructive Pulmonary Disease Patients With Chronic Hypercapnic Respiratory Failure.

Jian Xiao, Yan Wu, Limei Wang, Hong Zhou

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The clinical respiratory journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jian XiaoDepartment of Endocrinology, Chinese People's Liberation Army Western Theater Command General Hospital, Chengdu, Sichuan, China.
Yan WuDepartment of Respiratory and Critical Care Medicine, Chinese People's Liberation Army Western Theater Command General Hospital, Chengdu, Sichuan, China.
Limei WangDepartment of Respiratory and Critical Care Medicine, Chinese People's Liberation Army Western Theater Command General Hospital, Chengdu, Sichuan, China.
Hong ZhouDepartment of Respiratory and Critical Care Medicine, Chinese People's Liberation Army Western Theater Command General Hospital, Chengdu, Sichuan, China.ORCID https://orcid.org/0009-0001-4081-5672

Funding

Sichuan Province for Key Discipline-Respiratory Disease 41732D8/41C42D8
6 · The paper itself

Abstract

backgroundChronic obstructive pulmonary disease (COPD) is a progressive heterogeneous pulmonary disorder with an increasing high prevalence, particularly in the older. The objective of this study is to assess the effect of noninvasive ventilation combined with simultaneous nebulization during precise pulmonary rehabilitation nursing intervention in COPD patients with chronic hypercapnic respiratory failure, compared to pulmonary rehabilitation nursing alone.

methodsIn total, 240 elderly COPD patients with chronic hypercapnic respiratory failure were randomized controlled into either a precise pulmonary rehabilitation nursing model group (control group) or noninvasive ventilation coupled with simultaneous nebulization during pulmonary rehabilitation nursing (intervention group). For our evaluation, we considered general information, pulmonary function, exercise endurance, mental health, blood gas, inflammation, COPD severity, life quality, and overall efficacy of subjects before and on the 5-, 30-, 90-day intervention.

resultsThe total effective rates were 95% and 77.5% in the intervention and control group, respectively. In detail, the intervention group showed statistically significant improvements in lung function, exercise endurance, psychological health, blood gas inflammation, overall severity, and quality of life outcomes, especially on the 90-day intervention (p < 0.001).

conclusionsThe complex COPD patients with chronic hypercapnic respiratory failure may confer more gains from precise pulmonary rehabilitation nursing intervention combined with simultaneous inhalation therapy and noninvasive ventilation.

Indexed as

HypercapniaNoninvasive VentilationPulmonary Disease, Chronic ObstructiveRespiratory InsufficiencyRespiratory TherapyAdministration, InhalationAgedFemaleHumansMaleMiddle AgedQuality of LifeRespiratory Function TestsTreatment Outcomechronic hypercapnic respiratory failureCOPDinhalation therapynoninvasive ventilationpulmonary rehabilitation

Identifiers

PMID39909832
PMCPMC11798664

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.