Evidence map›Paper›PMID 39909707›Full record

Trial reportThe American journal of clinical nutrition2025

Efficacy of a 24-month behavioral intervention focused on sugary beverage reduction for Latino mother-infant dyads: evidence from a randomized controlled trial.

Christopher J Machle, Paige K Berger, Sarah-Jeanne Salvy, Claudia Rios, Ramon Durazo-Arvizu, Michael I Goran

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The American journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03141346 (Home Intervention for Reducing Sugary Drinks and Obesity in Hispanic Women-infants), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03141346 nacompletednot on this map

Home Intervention for Reducing Sugary Drinks and Obesity in Hispanic Women-infants

TypeinterventionalSponsorChildren's Hospital Los AngelesRan2017 to 2023Enrolled211ConditionsObesityArmsSugar reduction health education program, Control health education program, Home water delivery
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christopher J MachleDepartment of Pediatrics, Children's Hospital Los Angeles, Los Angeles, CA, United States; Department of Psychology, University of Oregon, Eugene, OR, United States.
Paige K BergerDepartment of Pediatrics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Sarah-Jeanne SalvyDepartment of Biomedical Sciences, Research Center for Health Equity, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Claudia RiosDepartment of Pediatrics, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Ramon Durazo-ArvizuThe Saban Research Institute, Biostatistics Core, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
Michael I GoranDepartment of Pediatrics, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States. Electronic address: goran@usc.edu.

Funding

Southern California Center for Chronic Health Disparities in Latino Children and Families.P50MD017344 · NIMHD · CHILDREN'S HOSPITAL OF LOS ANGELES · PI BOUTELLE, KERRI N · 2021 to 2025
$27.8M
Home intervention for reducing sugary drinks & obesity in Hispanic women-infantsR01DK109161 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GORAN, MICHAEL ISAAC · 2016 to 2021
$3.6M
Role of Human Milk Oligosaccharides on Infant Brain DevelopmentK99HD098288 · NICHD · CHILDREN'S HOSPITAL OF LOS ANGELES · PI BERGER, PAIGE KIMBERLY · 2020 to 2021
$180k
NICHD NIH HHS K99 HD098288NIDDK NIH HHS R01 DK109161NIMHD NIH HHS P50 MD017344
6 · The paper itself

Abstract

backgroundChildhood obesity disproportionately impacts marginalized and under-resourced communities, particularly Latinos. Although consumption of sugar-sweetened beverages and juices (SSBJs) in infancy is linked to increased obesity, few early-life interventions have targeted SSBJ reduction.

objectivesTo determine the efficacy of a culturally tailored home intervention for reducing SSBJ intake and obesity risk in Latino mothers and infants.

methodsMother-infant dyads (N = 210) were randomly assigned to 1 of 3 interventions for 2 years: 1) general health education (Control); 2) SSBJ intake reduction education (Intervention); 3) intervention plus home water delivery (Intervention + Water Delivery). Trained interventionists delivered education sessions 2 days/month during year 1 and 1 day/month during year 2. Mixed-effects models were used to examine changes in sugar consumption and weight-related outcomes over time by group for mothers and infants separately.

resultsThe mean prepregnancy BMI for mothers was 28.1 ± 5.6 kg/m

conclusionsThis intervention, combined with home delivery of bottled water, was effective in reducing sugar consumption from beverages for Latina mothers by roughly 8 g/day in the first year after childbirth. However, this effect was not maintained and was not significant for infants. More comprehensive and sustained strategies are likely needed to maintain efficacy and improve outcomes related to weight or body composition, particularly for infants. This trial was registered at clinicaltrials.gov as NCT03141346.

Indexed as

BeveragesHispanic or LatinoMothersPediatric ObesitySugar-Sweetened BeveragesAdultFemaleHumansInfantMaleYoung Adulthome-visit interventioninfantsLatinomothersobesitypreventionrandomized controlled trialsugar reduction

Identifiers

PMID39909707
PMCPMC11863324

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.