ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2025
Neurons of the Central Nucleus of the Amygdala That Express Angiotensin Type 2 Receptors Couple Lowered Blood Pressure with Anxiolysis in Male Mice.
Khalid Elsaafien, Matthew K Kirchner, Karen A Scott, Eliot A Spector, Francesca E Mowry, Colin Sumners, Javier E Stern, Annette D de Kloet, Eric G Krause
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1citing papers in PubMed
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1 · What the graph read from it
What it found
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2 · The registry
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5 · Who and what money
Authors and funding
9 authors.
Khalid ElsaafienNeuroscience Institute, College of Arts and Sciences, Georgia State University, Atlanta, Georgia 30303.
Matthew K KirchnerNeuroscience Institute, College of Arts and Sciences, Georgia State University, Atlanta, Georgia 30303.
Karen A ScottNeuroscience Institute, College of Arts and Sciences, Georgia State University, Atlanta, Georgia 30303.ORCID 0000-0002-4133-423X
Eliot A SpectorDepartments of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32610.
Francesca E MowryNeuroscience Institute, College of Arts and Sciences, Georgia State University, Atlanta, Georgia 30303.
Colin SumnersPhysiology and Aging, College of Medicine, University of Florida, Gainesville, Florida 32610.
Javier E SternNeuroscience Institute, College of Arts and Sciences, Georgia State University, Atlanta, Georgia 30303.
Annette D de KloetNeuroscience Institute, College of Arts and Sciences, Georgia State University, Atlanta, Georgia 30303 ekrause@gsu.edu adekloet@gsu.edu.
Eric G KrauseNeuroscience Institute, College of Arts and Sciences, Georgia State University, Atlanta, Georgia 30303 ekrause@gsu.edu adekloet@gsu.edu.
Funding
Interrogating stress-relieving neural circuits to alleviate cardiovascular diseaseR35HL150750 · NHLBI · UNIVERSITY OF FLORIDA · PI Eric Gerald Krause · 2020 to 2026
$5.9M
Neurons expressing angiotensin type 2 receptors in the NTS as an access point for cardiovascular control.R01HL136595 · NHLBI · UNIVERSITY OF FLORIDA · PI COLIN SUMNERS, Annette Diane de Kloet · 2018 to 2026
$4.8M
Interrogating distinct angiotensin type-1 and type-2 receptor containing brain circuits to understand and alleviate hypertensionR01HL145028 · NHLBI · UNIVERSITY OF FLORIDA · PI DE KLOET, ANNETTE DIANE · 2019 to 2023
$1.9M
Investigating Afferent Baroreflex Dysfunction in HypertensionK99HL175100 · NHLBI · GEORGIA STATE UNIVERSITY · PI EL SAAFIEN, KHALID · 2024 to 2024
Relief from psychological stress confers cardio-protection by altering brain activity and lowering blood pressure; however, the neuronal circuits orchestrating these effects are unknown. Here, we used male mice to discern neuronal circuits conferring stress relief and reduced blood pressure. We found that neurons residing in the central nucleus of the amygdala (CeA) expressing angiotensin type 2 receptors (AT
Indexed as
AnxietyBlood PressureCentral Amygdaloid NucleusNeuronsReceptor, Angiotensin, Type 2AnimalsMaleMiceMice, Inbred C57BLMice, TransgenicOptogeneticsStress, PsychologicalReceptor, Angiotensin, Type 2affectiveautonomicdepressionhypertensionmeditationstress
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Neurons of the Central Nucleus of the Amygdala That Express Angiotensin Type 2 Receptors Couple Lowered Blood Pressure with Anxiolysis in Male Mice. · full record | OpenQuestion