Evidence map›Paper›PMID 39909560›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2025

Kölliker's Organ Functions as a Developmental Hub in Mouse Cochlea Regulating Spiral Limbus and Tectorial Membrane Development.

Hongji Zhang, Timothy Papiernik, Selena Tian, Amal Yaghmour, Ahmad Alzein, James Benjamin Lennon, Rahul Maini, Xiaodong Tan, Ava Niazi, Joosang Park and 3 more

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hongji ZhangAnatomy Department, Midwestern University, Downers Grove, Illinois 60515.
Timothy PapiernikChicago College of Osteopathic Medicine, Midwestern University, Downers Grove, Illinois 60515.
Selena TianChicago College of Osteopathic Medicine, Midwestern University, Downers Grove, Illinois 60515.
Amal YaghmourCollege of Graduate Studies, Midwestern University, Downers Grove, Illinois 60515.
Ahmad AlzeinChicago College of Osteopathic Medicine, Midwestern University, Downers Grove, Illinois 60515.
James Benjamin LennonChicago College of Osteopathic Medicine, Midwestern University, Downers Grove, Illinois 60515.
Rahul MainiChicago College of Osteopathic Medicine, Midwestern University, Downers Grove, Illinois 60515.ORCID 0009-0008-9267-0058
Xiaodong TanDepartment of Otolaryngology, Feinberg School of Medicine Northwestern University, Chicago, Illinois 60611.
Ava NiaziNeuroscience Program, University of Utah, Salt Lake City, Utah 84112.
Joosang ParkDepartment of Neurobiology, University of Utah, Salt Lake City, Utah 84112.
Sungjin ParkDepartment of Neurobiology, University of Utah, Salt Lake City, Utah 84112.ORCID 0000-0003-4430-3305
Claus-Peter RichterDepartment of Otolaryngology, Feinberg School of Medicine Northwestern University, Chicago, Illinois 60611.
Michael EbeidAnatomy Department, Midwestern University, Downers Grove, Illinois 60515 mebeid@midwestern.edu.ORCID 0000-0003-1109-421X

Funding

Molecular mechanisms underlying morphogenesis of the tectorial membraneR01DC018814 · NIDCD · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI PARK, SUNG JIN · 2021 to 2025
$1.6M
NIDCD NIH HHS R01 DC018814
6 · The paper itself

Abstract

Kölliker's organ is a transient developmental structure in the mouse cochlea that undergoes significant remodeling postnatally. Utilizing an epithelial-specific conditional deletion mouse model of

Indexed as

CochleaTectorial MembraneTranscription FactorsAnimalsConnective Tissue Growth FactorDNA-Binding ProteinsFemaleMaleMiceMice, Inbred C57BLMice, KnockoutCCN2 protein, mouseConnective Tissue Growth FactorDNA-Binding ProteinsTranscription FactorscochleadevelopmentKölliker's organPrdm16spiral limbustectorial membrane

Identifiers

PMID39909560
PMCPMC11949483

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.