Evidence map›Paper›PMID 39909550›Full record

ReviewRegional anesthesia and pain medicine2025

Ten years of transitional pain service research and practice: where are we and where do we go from here?

Hance Clarke, Anna Waisman, Andrea Aternali, Kristina Axenova, Amjaad Almohawis, Kathryn Curtis, Joseph Fiorellino, Michelle Flynn, Praveen Ganty, Alexander Huang and 25 more

Abstract readReview
In one paragraph

Review in Regional anesthesia and pain medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Hance ClarkeAnesthesiology and Pain Medicine, University of Toronto, Toronto, Ontario, Canada hance.clarke@uhn.ca.ORCID 0000-0003-4975-3823
Anna WaismanPsychology, York University, Toronto, Ontario, Canada.
Andrea AternaliPsychology, York University, Toronto, Ontario, Canada.
Kristina AxenovaTransitional Pain Service, Toronto General Hospital, Toronto, Ontario, Canada.
Amjaad AlmohawisTransitional Pain Service, Toronto General Hospital, Toronto, Ontario, Canada.
Kathryn CurtisDepartment of Anesthesia and Pain Management, Toronto Western Hospital, Toronto, Ontario, Canada.
Joseph FiorellinoAnesthesiology and Pain Medicine, University of Toronto, Toronto, Ontario, Canada.
Michelle FlynnTransitional Pain Service, Toronto General Hospital, Toronto, Ontario, Canada.
Praveen GantyAnesthesiology and Pain Medicine, University of Toronto, Toronto, Ontario, Canada.
Alexander HuangAnesthesiology and Pain Medicine, University of Toronto, Toronto, Ontario, Canada.
Zhaorong HongTransitional Pain Service, Toronto General Hospital, Toronto, Ontario, Canada.
Rita KatznelsonAnesthesiology and Pain Medicine, University of Toronto, Toronto, Ontario, Canada.
Yuvaraj KotteeswaranAnesthesia, Northern Ontario School of Medicine University, Thunder Bay, Ontario, Canada.
Salima LadakTransitional Pain Service, Toronto General Hospital, Toronto, Ontario, Canada.
Karim S LadhaAnesthesiology and Pain Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0001-7303-2458
Anna LomanowskaTransitional Pain Service, Toronto General Hospital, Toronto, Ontario, Canada.
Heather Lumsden-RueggPsychology, York University, Toronto, Ontario, Canada.
Ala MahamidTransitional Pain Service, Toronto General Hospital, Toronto, Ontario, Canada.
Molly McCarthyTransitional Pain Service, Toronto General Hospital, Toronto, Ontario, Canada.
Sarah MilesTransitional Pain Service, Toronto General Hospital, Toronto, Ontario, Canada.
Judith NichollsAnesthesia, George Town Hospital, George Town, Cayman Islands.
M Gabrielle PagéResearch Center, CHUM, Montreal, Quebec, Canada.ORCID 0000-0002-7742-2717
Miki PeerTransitional Pain Service, Toronto General Hospital, Toronto, Ontario, Canada.
Brittany N RosenbloomAnesthesiology and Pain Medicine, University of Toronto, Toronto, Ontario, Canada.
Daniel Santa MinaDepartment of Anesthesia and Pain Management, Toronto General Hospital, Toronto, Ontario, Canada.
Rachel SiegalTransitional Pain Service, Toronto General Hospital, Toronto, Ontario, Canada.
P Maxwell SlepianAnesthesiology and Pain Medicine, University of Toronto, Toronto, Ontario, Canada.
Ainsley SutherlandDepartment of Anesthesiology, Pharmacology & Therapeutics, The University of British Columbia, Vancouver, British Columbia, Canada.
Diana TamirAnesthesiology and Pain Medicine, University of Toronto, Toronto, Ontario, Canada.
Leeping TaoTransitional Pain Service, Toronto General Hospital, Toronto, Ontario, Canada.
Paul TumberAnesthesiology and Pain Medicine, University of Toronto, Toronto, Ontario, Canada.
Jeffrey WieskopfTransitional Pain Service, Toronto General Hospital, Toronto, Ontario, Canada.
Callon WilliamsTransitional Pain Service, Toronto General Hospital, Toronto, Ontario, Canada.
Elizabeth WoodfordTransitional Pain Service, Toronto General Hospital, Toronto, Ontario, Canada.
Joel KatzAnesthesiology and Pain Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-8686-447X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic postsurgical pain (CPSP) is a prevalent yet unintended consequence of surgery with substantial burdens to the individual and their family, the healthcare system, and society at large. The present article briefly reviews the evidence for transitional pain services (TPSs) that have arisen in an effort to prevent and mange CPSP and persistent opioid use, and provides an update on recent novel risk factors for CPSP. Available evidence from one randomized controlled trial (RCT) and three non-randomized cohort studies suggests that TPS treatment is associated with better opioid use outcomes, including fewer opioid tablets prescribed at discharge, better opioid weaning results, a lower incidence of new-onset chronic opioid use, and lower consumption of opioids even at later time points up to 1 year after surgery. Another RCT indicates TPS treatment can be enhanced by provision of perioperative clinical hypnosis. While these preliminary studies are generally positive, large-scale, RCTs are needed to provide a more definitive picture of whether TPSs are effective in reducing opioid consumption and improving pain and mental health outcomes in the short and long term. With the expansion of TPSs across North America and globally, perioperative care focused on reducing the transition to pain chronicity has the potential to help millions of patients. With additional evidence from well-controlled RCTs, TPSs are well poised to continue to evolve and strengthen the role of multidisciplinary care teams in the immediate postdischarge period and beyond.

Indexed as

Chronic PainPain ClinicsPain ManagementPostoperative PainTransitional CareAnalgesics, OpioidHumansOpioid-Related DisordersRandomized Controlled Trials as TopicAnalgesics, OpioidAcute PainCHRONIC PAINPain ManagementPain, Postoperative

Identifiers

PMID39909550
PMCPMC11877109

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.