Evidence map›Paper›PMID 39909546›Full record

SynthesisRegional anesthesia and pain medicine2025

Prevalence of and recommendation for measuring chronic postsurgical pain in children: an updated systematic review and meta-analysis.

Brittany N Rosenbloom, Simona Denise Frederiksen, Vienna Wang, Kathryn A Birnie, Christine S Park, Grace Gordon, Nivez Rasic, Jennifer N Stinson, Jennifer A Rabbitts

Registry-linked trialAbstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Regional anesthesia and pain medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07629362 (Chronic Postoperative Pain After Appendectomy), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07629362 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Chronic Postoperative Pain After Appendectomy: A Prospective Observational Study

Typeobservational_patient_registrySponsorKocaeli City HospitalRan2026 to 2027Enrolled231ConditionsChronic Pain, Postoperative, Quality of Life, Functional Ability, Appendectomy
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Observational
  5. An Update on Pain Management in Pediatric Spine Surgery.Current reviews in musculoskeletal medicine · 2026
    Review
  6. Observational
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Brittany N RosenbloomToronto Academic Pain Medicine Institute, Women's College Hospital, Toronto, Ontario, Canada brittany.rosenbloom@wchospital.ca.
Simona Denise FrederiksenAlberta Health Services Health Systems Evaluation and Evidence, Calgary, Alberta, Canada.
Vienna WangDepartment of Anesthesiology, Perioperative, and Pain Medicine, Stanford University School of Medicine, Stanford, California, USA.
Kathryn A BirnieDepartment of Anesthesiology, Perioperative, and Pain Medicine, University of Calgary, Calgary, Alberta, Canada.
Christine S ParkDentistry, University of Washington, Seattle, Washington, USA.
Grace GordonCenter for Child Health, Behavior and Development, Seattle Children's Research Institute, Seattle, Washington, USA.
Nivez RasicDepartment of Anesthesiology, Perioperative, and Pain Medicine, University of Calgary, Calgary, Alberta, Canada.
Jennifer N StinsonThe Hospital for Sick Children Child Health Evaluative Sciences, Toronto, Ontario, Canada.
Jennifer A RabbittsStanford University School of Medicine, Stanford, California, USA.ORCID 0000-0002-5881-4045

Funding

Preventing the Transition from Acute to Chronic Musculoskeletal Pain in Adolescents after Surgery: The Role of SleepK24AR080786 · NIAMS · STANFORD UNIVERSITY · PI Jennifer Rabbitts · 2023 to 2026
$712k
NIAMS NIH HHS K24 AR080786
6 · The paper itself

Abstract

backgroundAccording to the prior 2017 review (Rabbitts

objectiveThe aims of this current review were to: (1) provide an updated prevalence estimate for pediatric CPSP and (2) examine definitions of pediatric CPSP applied in current research. EVIDENCE REVIEW: Prospective, observational studies examining CPSP using a validated self-report pain intensity measure in children were included. 4884 unique publications were screened with 20 articles meeting inclusion criteria. Risk of bias using Quality in Prognostic Study tool ranged from low to high.

findingsThe pooled prevalence of CPSP among mostly major surgeries was 28.2% (95% CI 21.4% to 36.1%). Subgroup analysis of spinal fusion surgeries identified a prevalence of 31% (95% CI 21.4% to 43.5%). Using Grading of Recommendations, Assessment, Development, and Evaluation, the certainty in prevalence estimates was moderate. Studies used a range of valid pain intensity measures to classify CPSP (eg, Numeric Rating Scale), often without pain interference or quality of life measures.

conclusionsThe overall prevalence of pediatric CPSP is higher than estimated in the prior review, and quality of studies generally improved though with some heterogeneity. Standardizing the measurement of CPSP will facilitate future efforts to combine and compare data across studies. PROSPERO REGISTRATION NUMBER: CRD42022306340.

Indexed as

Chronic PainPain MeasurementPostoperative PainPractice Guidelines as TopicAdolescentChildHumansObservational Studies as TopicPrevalenceCHRONIC PAINPain, PostoperativePediatrics

Identifiers

PMID39909546
PMCPMC11804871

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.